Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
about
Cardiolipin Interactions with ProteinsACFIS: a web server for fragment-based drug discoveryComparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitorProtein crystallography and fragment-based drug design.Current challenges and trends in the discovery of agrochemicals.Advances in the design of a multipurpose fragment screening library.Computational and experimental insights into the mechanism of substrate recognition and feedback inhibition of protoporphyrinogen oxidase.Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand ComplexesStructural basis of resistance to anti-cytochrome bc₁ complex inhibitors: implication for drug improvementCrystal Structure and Function of PqqF Protein in the Pyrroloquinoline Quinone Biosynthetic Pathway.Hot-spot identification on a broad class of proteins and RNA suggest unifying principles of molecular recognition.Trypsin-Ligand binding affinities calculated using an effective interaction entropy method under polarized force field.Mitochondrial complex III Rieske Fe-S protein processing and assembly.Identification of a New Isoindole-2-yl Scaffold as a Qo and Qi Dual Inhibitor of Cytochrome bc 1 Complex: Virtual Screening, Synthesis, and Biochemical Assay.Computational design of novel inhibitors to overcome weed resistance associated with acetohydroxyacid synthase (AHAS) P197L mutant.UQCRFS1N assembles mitochondrial respiratory complex-III into an asymmetric 21-subunit dimer.Structure based in silico identification of potentially non-steroidal brassinosteroids mimics.Novel Mcl-1/Bcl-2 dual inhibitors created by the structure-based hybridization of drug-divided building blocks and a fragment deconstructed from a known two-face BH3 mimetic.Chlorophyll a is the crucial redox sensor and transmembrane signal transmitter in the cytochrome b6f complex. Components and mechanisms of state transitions from the hydrophobic mismatch viewpoint.Optical waveguide based on a polarized polydiacetylene microtube.Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization.X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery.
P2860
Q28389105-47D90BAA-8AFB-483C-8E4D-9B728649D376Q28830078-F922B94D-F350-483C-8610-ADE29584BF08Q28830547-6341CD27-5055-4C5C-8AFE-897065F15AFDQ34353117-B7738AB8-3014-494D-BEDB-F6D530A90F9DQ34364424-8AED6535-E76D-4CE3-9520-9CD850C98754Q34616596-AA77F913-BB25-4B82-A98F-9E41E592849DQ34919428-29490458-0937-4A7C-9D04-0F923BB067D5Q36096683-4C764084-FDAC-4F6A-B3F9-9D11F097689DQ36677835-869D82E1-BF28-4536-A179-88B442F696DFQ37117280-4748B449-EBC3-43B4-A46A-8F6E1E67F79AQ41512122-D3A7337A-09CA-4121-8F1E-1576C135898CQ47129892-760A3F1A-DB3E-430E-B88F-F492ED071CE6Q47290712-0BBA9A8E-1C25-4AA3-8A5C-F4EC48105445Q47770268-E2B124AE-38EF-437E-9A5F-88364B205073Q51136849-A438015B-D0E5-4094-8707-C67781907B7CQ52364960-E0FE1700-E4BE-40A9-804E-0862A50804C0Q52640532-2E7EA5BB-1020-4F03-9FF1-D6F4B3A42C84Q52970803-EE821119-D9B8-42FD-B5F5-02D676DEF014Q53187558-324311FA-B5DC-4402-ABD4-4A20242B84A5Q53618676-81874CB5-CF54-4FA9-AE9B-650E1E4D0CE7Q54425083-258781DC-36FB-4E3C-9154-ECC28DA17762Q55004502-37A0499E-3985-45F9-A19C-818A4A9CB45D
P2860
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@ast
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@en
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@nl
type
label
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@ast
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@en
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@nl
prefLabel
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@ast
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@en
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@nl
P2093
P3181
P356
P1476
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex
@en
P2093
Edward A Berry
Ge-Fei Hao
Guang-Fu Yang
Jia-Wei Wu
Li-Shar Huang
Wen-Chao Yang
Xiao-Lei Zhu
P304
P3181
P356
10.1021/JA3001908
P407
P577
2012-07-11T00:00:00Z