Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
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The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformationEvidence that phosphorylation of threonine in the GT motif triggers activation of PknA, a eukaryotic-type serine/threonine kinase from Mycobacterium tuberculosisCross-phosphorylation of bacterial serine/threonine and tyrosine protein kinases on key regulatory residuesA novel STK1-targeted small-molecule as an "antibiotic resistance breaker" against multidrug-resistant Staphylococcus aureus.Identification of novel potential antibiotics against Staphylococcus using structure-based drug screening targeting dihydrofolate reductaseBacterial cell division regulation by Ser/Thr kinases: a structural perspectiveProtein-serine/threonine/tyrosine kinases in bacterial signaling and regulation.Role of eukaryotic-like serine/threonine kinases in bacterial cell division and morphogenesis.Zinc regulates the activity of kinase-phosphatase pair (BasPrkC/BasPrpC) in Bacillus anthracis.Autophosphorylation Mechanism of the Ser/Thr Kinase Stk1 From Staphylococcus aureus.Metabolic conversion of CI-1040 turns a cellular MEK-inhibitor into an antibacterial compound.The serine/threonine kinase Stk and the phosphatase Stp regulate cell wall synthesis in Staphylococcus aureus
P2860
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P2860
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
description
2012 nî lūn-bûn
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2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@ast
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@en
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@nl
type
label
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@ast
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@en
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@nl
prefLabel
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@ast
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@en
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@nl
P2093
P2860
P1433
P1476
Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
@en
P2093
Knut Ohlsen
Sonja Rakette
Stefanie Donat
P2860
P304
P356
10.1371/JOURNAL.PONE.0039136
P407
P50
P577
2012-01-01T00:00:00Z