Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition - Wikidata - wikimedia - TriplyDB

Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

http://www.wikidata.org/entity/Q27681491

about

Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain.N(ω)-NITRO-N(ω')-SUBSTITUTED GUANIDINES: A SIMPLE CLASS OF NITRIC OXIDE SYNTHASE INHIBITORS.Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus.2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.Nitric oxide synthase and structure-based inhibitor design.The latest advances in the discovery of nitric oxide hybrid drug compounds.Fluorination Effects on NOS Inhibitory Activity of Pyrazoles Related to Curcumin.Structures of human constitutive nitric oxide synthases.Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.Synthesis and biological evaluation of novel tricyclic matrinic derivatives as potential anti-filovirus agents Copper-catalyzed synthesis of quinoline derivatives via tandem Knoevenagel condensation, amination and cyclization

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P2860

Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

http://www.wikidata.org/entity/Q27681491

description

2014 nî lūn-bûn

@nan

2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@ast

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@en

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@nl

type

label

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@ast

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@en

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@nl

prefLabel

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@ast

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@en

Simplified 2-Aminoquinoline-Ba ...... tric Oxide Synthase Inhibition

@nl

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Journal of Medicinal Chemistry

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Simplified 2-aminoquinoline-ba ...... tric oxide synthase inhibition

@en

P2093

Georges Chreifi

http://www.w3.org/2001/XMLSchema#string

Huiying Li

http://www.w3.org/2001/XMLSchema#string

Linda J Roman

http://www.w3.org/2001/XMLSchema#string

Maris A Cinelli

http://www.w3.org/2001/XMLSchema#string

Richard B Silverman

http://www.w3.org/2001/XMLSchema#string

Thomas L Poulos

http://www.w3.org/2001/XMLSchema#string

P2860

Nitric oxide synthases in mammals

The novel binding mode of N-alkyl-N'-hydroxyguanidine to neuronal nitric oxide synthase provides mechanistic insights into NO biosynthesis

Minimal Pharmacophoric Elements and Fragment Hopping, an Approach Directed at Molecular Diversity and Isozyme Selectivity. Design of Selective Neuronal Nitric Oxide Synthase Inhibitors

Unexpected Binding Modes of Nitric Oxide Synthase Inhibitors Effective in the Prevention of a Cerebral Palsy Phenotype in an Animal Model

Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase

Peripheral but crucial: A hydrophobic pocket (Tyr706, Leu337, and Met336) for potent and selective inhibition of neuronal nitric oxide synthase

Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives

From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)

Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase

Intramolecular hydrogen bonding: A potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase

P304

1513-1530

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scholarly article

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10.1021/JM401838X

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4

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57

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2014-02-10T00:00:00Z

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259958746

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24472039

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3954451

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