Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis
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Anatomy of enzyme channelsThe structure of human 15-lipoxygenase-2 with a substrate mimicThe role of lipoxygenases in pathophysiology; new insights and future perspectivesStructure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosaMammalian lipoxygenases and their biological relevanceThe structural basis for specificity in lipoxygenase catalysis.Crystal structure of a lipoxygenase in complex with substrate: the arachidonic acid-binding site of 8R-lipoxygenase.Importance of protein dynamics during enzymatic C-H bond cleavage catalysis.Fluctuations of an exposed π-helix involved in lipoxygenase substrate recognitionAn iron 13S-lipoxygenase with an α-linolenic acid specific hydroperoxidase activity from Fusarium oxysporum.Antitumor Activities of Ethyl Acetate Extracts from Selaginella doederleinii Hieron In Vitro and In Vivo and Its Possible Mechanism.Enzyme Tunnels and Gates As Relevant Targets in Drug Design.Locating a lipid at the portal to the lipoxygenase active siteIdentification of the Substrate Access Portal of 5-LipoxygenaseFunctional characterization of genetic enzyme variations in human lipoxygenases.Industrial potential of lipoxygenases.Crystallization and preliminary crystallographic analysis of manganese lipoxygenaseMolecular Dynamics Study on the Apo- and Holo-forms of 5-Lipoxygenase.Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency.Crystal Structure of Manganese Lipoxygenase of the Rice Blast Fungus Magnaporthe oryzae.Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSISWater-soluble Fe(II)-H2O complex with a weak O-H bond transfers a hydrogen atom via an observable monomeric Fe(III)-OH.Lipoxygenase 2 from Cyanothece sp. controls dioxygen insertion by steric shielding and substrate fixation.Inflammation, Cancer and Oxidative Lipoxygenase Activity are Intimately Linked.PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.Enzymatic Studies of Isoflavonoids as Selective and Potent Inhibitors of Human Leukocyte 5-Lipo-Oxygenase.Structural Dynamics of 15-Lipoxygenase-2 via Hydrogen-Deuterium Exchange.
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P2860
Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis
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2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@ast
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@en
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@nl
type
label
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@ast
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@en
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@nl
prefLabel
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@ast
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@en
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@nl
P2093
P2860
P1433
P1476
Crystal structure of 12-lipoxy ...... -binding channel for catalysis
@en
P2093
Lawrence J Marnett
Max O Funk
Timothy C Mueser
P2860
P304
P356
10.1016/J.STR.2012.06.003
P407
P50
P577
2012-07-12T00:00:00Z