An autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis
about
Regulation of mTORC1 by PI3K signalingStructural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein MiroStructure-guided Mutation of the Conserved G3-box Glycine in Rheb Generates a Constitutively Activated Regulator of Mammalian Target of Rapamycin (mTOR)Molecular genetics of clear-cell renal cell carcinomaThe mitochondrial Ras-related GTPase Miro: views from inside and outside the metazoan kingdom.Recent progress in the study of the Rheb family GTPases.Small GTPases in C. elegans metabolism.Point mutations of the mTOR-RHEB pathway in renal cell carcinoma.Inhibition of MAPK pathway is essential for suppressing Rheb-Y35N driven tumor growth.Evolutionary Conservation of the Components in the TOR Signaling Pathways.Amino acid and small GTPase regulation of mTORC1.An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation.Overexpression of Na+/Mg2+ exchanger SLC41A1 attenuates pro-survival signaling.Mechanistic Insights into the Differential Catalysis by RheB and Its Mutants: Y35A and Y35A-D65A.
P2860
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P2860
An autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@ast
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@en
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@nl
type
label
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@ast
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@en
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@nl
prefLabel
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@ast
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@en
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@nl
P2093
P50
P1433
P1476
An autoinhibited noncanonical ...... b maintains mTORC1 homeostasis
@en
P2093
Noboru Ishiyama
Vanessa Di Palma
P304
P356
10.1016/J.STR.2012.06.013
P577
2012-09-05T00:00:00Z