The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions - Wikidata - wikimedia - TriplyDB

The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions

The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions

http://www.wikidata.org/entity/Q27682197

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LipidII: Just Another Brick in the Wall?Distinct mechanisms contribute to immunity in the lantibiotic NAI-107 producer strain Microbispora ATCC PTA-5024 A relA-dependent regulatory cascade for auto-induction of microbisporicin production in Microbispora corallina Depletion of Undecaprenyl Pyrophosphate Phosphatases Disrupts Cell Envelope Biogenesis in Bacillus subtilis.The sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa.In vivo pharmacokinetics and pharmacodynamics of the lantibiotic NAI-107 in a neutropenic murine thigh infection model.Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024.Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis.The Lantibiotic NAI-107 Efficiently Rescues Drosophila melanogaster from Infection with Methicillin-Resistant Staphylococcus aureus USA300.Growing the seeds sown by Piero Sensi.Advancing cell wall inhibitors towards clinical applications.Targeting bactoprenol-coupled cell envelope precursors.Pharmacological and pharmacokinetic properties of lanthipeptides undergoing clinical studies.Macromolecule Biosynthesis Assay and Fluorescence Spectroscopy Methods to Explore Antimicrobial Peptide Mode(s) of Action.Targeting a cell wall biosynthesis hot spot.VraH Is the Third Component of the Staphylococcus aureus VraDEH System Involved in Gallidermin and Daptomycin Resistance and Pathogenicity.Extraction and Analysis of Peptidoglycan Cell Wall Precursors.LsbB Bacteriocin Interacts with the Third Transmembrane Domain of the YvjB Receptor Ribosomal Natural Products, Tailored To Fit.Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells.Determination of Structure and Micellar Interactions of Small Antimicrobial Peptides by Solution-State NMR.Antibakterielle Strategien und bakterielle Abwehrmechanismen

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The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions

http://www.wikidata.org/entity/Q27682197

description

2014 nî lūn-bûn

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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2014 թվականի ապրիլին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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The Lantibiotic NAI-107 Binds ...... and Impairs Membrane Functions

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JBC.M113.537449

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Journal of Biological Chemistry

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The Lantibiotic NAI-107 Binds ...... and Impairs Membrane Functions

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Anna Müller

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Bastian Kohl

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Hans-Georg Sahl

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Sonia Maffioli

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Stefano Donadio

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Torsion angle dynamics for NMR structure calculation with the new program DYANA

Identification and in vitro analysis of the GatD/MurT enzyme-complex catalyzing lipid II amidation in Staphylococcus aureus

Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field

Membrane potential is important for bacterial cell division

Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity.

A novel lantibiotic acting on bacterial cell wall synthesis produced by the uncommon actinomycete Planomonospora sp.

Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes.

Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

In vitro assembly of a complete, pentaglycine interpeptide bridge containing cell wall precursor (lipid II-Gly5) of Staphylococcus aureus.

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scholarly article

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10.1074/JBC.M113.537449

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17

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289

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Julia Elisabeth Bandow

Reinhard Wimmer

Michaela Wenzel

Tanja Schneider

Margherita Sosio

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2014-04-25T00:00:00Z

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24627484

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4002112

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