Structural insights into the mechanism and inhibition of the β-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa
about
Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosaTrapping the dynamic acyl carrier protein in fatty acid biosynthesisA Double-Hotdog with a New Trick: Structure and Mechanism of the trans -Acyltransferase Polyketide Synthase Enoyl-isomeraseUsing modern tools to probe the structure-function relationship of fatty acid synthasesMolecular basis for the inhibition of β-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.A Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabAFabQ, a dual-function dehydratase/isomerase, circumvents the last step of the classical fatty acid synthesis cycle.Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents.The chain-flipping mechanism of ACP (acyl carrier protein)-dependent enzymes appears universal.Using bacterial genomes and essential genes for the development of new antibiotics.Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa.Structural analysis of the dual-function thioesterase SAV606 unravels the mechanism of Michael addition of glycine to an α,β-unsaturated thioester.
P2860
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P2860
Structural insights into the mechanism and inhibition of the β-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa
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2013 nî lūn-bûn
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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural insights into the m ...... se from Pseudomonas aeruginosa
@ast
Structural insights into the m ...... se from Pseudomonas aeruginosa
@en
Structural insights into the m ...... se from Pseudomonas aeruginosa
@nl
type
label
Structural insights into the m ...... se from Pseudomonas aeruginosa
@ast
Structural insights into the m ...... se from Pseudomonas aeruginosa
@en
Structural insights into the m ...... se from Pseudomonas aeruginosa
@nl
prefLabel
Structural insights into the m ...... se from Pseudomonas aeruginosa
@ast
Structural insights into the m ...... se from Pseudomonas aeruginosa
@en
Structural insights into the m ...... se from Pseudomonas aeruginosa
@nl
P2093
P50
P1476
Structural insights into the m ...... se from Pseudomonas aeruginosa
@en
P2093
Alessa Koehnke
Fraser G Duthie
Magnus S Alphey
Stephen A McMahon
Stuart M Leckie
P304
P356
10.1016/J.JMB.2012.11.017
P407
P577
2013-01-23T00:00:00Z