Inhibiting NF-κB-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structures
about
Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB.NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis.TWEAK/Fn14 and Non-Canonical NF-kappaB Signaling in Kidney DiseaseMechanisms and consequences of constitutive NF-κB activation in B-cell lymphoid malignancies.Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?Mitogen-Activated Protein Kinase 14 Promotes AKI.Targeting non-canonical nuclear factor-κB signalling attenuates neovascularization in a novel 3D model of rheumatoid arthritis synovial angiogenesis.Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity.NF-kB2 induces senescence bypass in melanoma via a direct transcriptional activation of EZH2.
P2860
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P2860
Inhibiting NF-κB-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structures
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@ast
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@en
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@nl
type
label
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@ast
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@en
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@nl
prefLabel
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@ast
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@en
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@nl
P2093
P1476
Inhibiting NF-κB-inducing kina ...... hip, and co-crystal structures
@en
P2093
Athena Sudom
Ben Fisher
Bohdan Waszkowycz
Ellyn Farrelly
Guoqing Chen
Jinsong Liu
John Eksterowicz
Lawrence R McGee
P304
P356
10.1016/J.BMCL.2013.01.012
P407
P577
2013-03-01T00:00:00Z