Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
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Functional and Structural Analysis of Influenza Virus Neuraminidase N3 Offers Further Insight into the Mechanisms of Oseltamivir ResistanceCharacterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza virusesStructure of Influenza Virus N7: the Last Piece of the Neuraminidase"Jigsaw"PuzzleTuning mechanism-based inactivators of neuraminidases: mechanistic and structural insightsThe catalytic mechanism of human parainfluenza virus type 3 haemagglutinin-neuraminidase revealedFrom neuraminidase inhibitors to conjugates: a step towards better anti-influenza drugs?6SLN-lipo PGA specifically catches (coats) human influenza virus and synergizes neuraminidase-targeting drugs for human influenza therapeutic potential.The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.Indirect study of non-covalent protein complexes by MALDI mass spectrometry: Origins, advantages, and applications of the "intensity-fading" approach.Dissecting conformational contributions to glycosidase catalysis and inhibition.pKa cycling of the general acid/base in glycoside hydrolase families 33 and 34.Learning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza.Bifunctional thiosialosides inhibit influenza virus.A sialosyl sulfonate as a potent inhibitor of influenza virus replication.Simple, rapid detection of influenza A (H1N1) viruses using a highly sensitive peptide-based molecular beacon.Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality.Atypical group 1 neuraminidase pH1N1-N1 bound to a group 1 inhibitor.
P2860
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P2860
Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
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Influenza neuraminidase operat ...... argeted by covalent inhibitors
@ast
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@en
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@nl
type
label
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@ast
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@en
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@nl
prefLabel
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@ast
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@en
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@nl
P2093
P2860
P356
P1476
Influenza neuraminidase operat ...... argeted by covalent inhibitors
@en
P2093
Christopher J Vavricka
Hiromasa Kiyota
Jianxun Qi
Jinghua Yan
Kosuke Tanaka
Nongluk Sriwilaijaroen
Yasuo Suzuki
P2860
P2888
P356
10.1038/NCOMMS2487
P407
P577
2013-01-01T00:00:00Z
P6179
1002009031