Fragment-based ligand design of novel potent inhibitors of tankyrases

Fragment-based ligand design of novel potent inhibitors of tankyrases

Item
http://www.wikidata.org/entity/Q27684619
Design, Synthesis, Crystallographic Studies, and Preliminary Biological Appraisal of New Substituted Triazolo[4,3- b ]pyridazin-8-amine Derivatives as Tankyrase InhibitorsFragment-based strategy for structural optimization in combination with 3D-QSAR.Scaffold hopping approach on the route to selective tankyrase inhibitors.Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics.Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase InhibitorsStructural Implications for Selective Targeting of PARPs.Tankyrases as drug targets.Tankyrases: structure, function and therapeutic implications in cancer.Recent advances in the structure-based rational design of TNKSIs.Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors.Palladium-Catalyzed [3+3] Annulation between Diarylamines and α,β-Unsaturated Acids through CH Activation: Direct Access to 4-Substituted 2-Quinolinones.Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.Toxoplasma calcium-dependent protein kinase 1 inhibitors: probing activity and resistance using cellular thermal shift assays.
P2860

Fragment-based ligand design of novel potent inhibitors of tankyrases

Item
http://www.wikidata.org/entity/Q27684619
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Fragment-based ligand design of novel potent inhibitors of tankyrases
@ast
Fragment-based ligand design of novel potent inhibitors of tankyrases
@en
Fragment-based ligand design of novel potent inhibitors of tankyrases
@nl
type
label
Fragment-based ligand design of novel potent inhibitors of tankyrases
@ast
Fragment-based ligand design of novel potent inhibitors of tankyrases
@en
Fragment-based ligand design of novel potent inhibitors of tankyrases
@nl
prefLabel
Fragment-based ligand design of novel potent inhibitors of tankyrases
@ast
Fragment-based ligand design of novel potent inhibitors of tankyrases
@en
Fragment-based ligand design of novel potent inhibitors of tankyrases
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Fragment-based ligand design of novel potent inhibitors of tankyrases
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698