Structural insights into RIP3-mediated necroptotic signaling
about
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKLPost-translational modifications as key regulators of TNF-induced necroptosisAn outline of necrosome triggersRegulation of tumour necrosis factor signalling: live or let diePpm1b negatively regulates necroptosis through dephosphorylating Rip3Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosisTranslocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell deathPseudokinases: update on their functions and evaluation as new drug targets.Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation.Structural assembly of the signaling competent ERK2-RSK1 heterodimeric protein kinase complex.Suppression of RIP3-dependent necroptosis by human cytomegalovirusThe ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosisUsing Small Molecules to Dissect Non-apoptotic Programmed Cell Death: Necroptosis, Ferroptosis, and Pyroptosis.Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.Structural Basis for the Non-catalytic Functions of Protein Kinases.Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell deathSequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis.Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis.Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM KinasesTNF-α sensitizes chemotherapy and radiotherapy against breast cancer cells.True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity.Ars Moriendi; the art of dying well - new insights into the molecular pathways of necroptotic cell death.Structural basis of cell apoptosis and necrosis in TNFR signaling.Live to die another way: modes of programmed cell death and the signals emanating from dying cells.A tale of two domains - a structural perspective of the pseudokinase, MLKL.Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity.Necroptosis: a potential, promising target and switch in acute pancreatitis.Nucleotide-binding mechanisms in pseudokinases.Necrosome core machinery: MLKL.Generation of small molecules to interfere with regulated necrosis.Insane in the membrane: a structural perspective of MLKL function in necroptosis.The Inflammatory Signal Adaptor RIPK3: Functions Beyond Necroptosis.Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis.The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process.Initiation and execution mechanisms of necroptosis: an overview.ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences.Shikonin induces apoptosis and necroptosis in pancreatic cancer via regulating the expression of RIP1/RIP3 and synergizes the activity of gemcitabine.MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis.Fuzziness enables context dependence of protein interactions.
P2860
Q24339564-23F03B0F-A53E-4322-B39F-34160F9EC369Q26744244-D5995FD8-421D-4BE7-9942-3B181454809EQ26751108-740DA0F9-6525-4817-8C23-A2537A18251FQ28262381-CAC9883F-0CB1-453F-97BC-0A6CCDEBBFD5Q28645752-03B0D931-FF70-426F-87FE-8C9BDC01666BQ28654331-6E7A846B-B0EC-4BA3-852E-A3CE6D5271C5Q28660873-509CE610-165C-4239-AB9F-9F91A86252FEQ30397636-600D7A63-08D2-4B29-9152-18A9C4FD9CA1Q35044718-EC9CAF23-EEA0-4065-BFE8-158BD9FDBD3AQ35157014-7542776D-4EEF-4868-B489-093CE3C742EBQ35561085-FB034ECF-BD94-4E6A-8553-C8558FBC9277Q35630131-5C36D70F-2A4B-4615-8754-4CCD24973738Q35781653-550BA277-B8F8-450B-93BF-694929AAE2C0Q36084130-BD5709E9-D0C3-476D-9FED-D84A77FECD55Q36381630-6EC23F18-757F-428F-8596-F14D1909ED59Q36446161-7930FFB1-BA26-4930-8BC9-6B489F625FE6Q36497425-C399BF9E-F74D-4D00-9B83-A5C8F2444B85Q36626724-DE40EEC5-0A05-4613-8AA8-CC415D95E9C2Q36751262-A6F2E03A-994D-4546-B482-3A5F5B8CA87CQ36881939-F92D75DD-A5A7-47C7-A096-72177899ECE4Q37602579-9F1C2458-CB45-4EF1-928B-7668C4B98E79Q37603408-1F90895B-C256-49AB-9868-E8396A90BF5FQ38182403-72977E8F-71D1-4F5B-9908-D834CE070050Q38275782-B3EE38CC-3B04-4EA2-B76B-C04024278E1EQ38492529-D5DED6F3-F4C1-406D-B911-7F637ACB1335Q38580336-02C321A9-5188-4C2D-95C2-EF2F8163A2F2Q38589407-01D3675B-4B60-4FD2-AD68-B48992B52561Q38619561-4F9CED64-699A-441F-A499-E36809647F19Q38641286-43E74F43-6472-4522-B2C0-320E93198B81Q38799137-3093EA19-5CEF-4A1B-B7A2-034C89637220Q38799144-B76BDFEA-FD60-43FD-9E99-0FBBDB1F4139Q39044985-7BD75118-C7AC-4111-BB27-F8D6B339D409Q39077160-B937C946-EC96-4757-A04B-B45EA9EE72B3Q39105381-ADA31C98-2E2C-4C52-9404-C3D32DFA5335Q39128473-E25225AD-EF60-4167-9CBF-3C5073B22785Q39302537-4C0BAE9E-CFE5-4268-972F-CFBFDD65E111Q42801479-E7D85540-6E4F-44A6-A7B8-D07B05D6B615Q47377758-BE93036E-A7BD-4434-92B0-8946C3C5BD4EQ47924975-ABC8F2AB-0474-4A5F-BCEE-BC4CE473E2CDQ48005558-55E89046-B406-49C9-B0DF-B24B304C35BD
P2860
Structural insights into RIP3-mediated necroptotic signaling
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural insights into RIP3-mediated necroptotic signaling
@ast
Structural insights into RIP3-mediated necroptotic signaling
@en
Structural insights into RIP3-mediated necroptotic signaling
@nl
type
label
Structural insights into RIP3-mediated necroptotic signaling
@ast
Structural insights into RIP3-mediated necroptotic signaling
@en
Structural insights into RIP3-mediated necroptotic signaling
@nl
prefLabel
Structural insights into RIP3-mediated necroptotic signaling
@ast
Structural insights into RIP3-mediated necroptotic signaling
@en
Structural insights into RIP3-mediated necroptotic signaling
@nl
P2093
P3181
P1433
P1476
Structural insights into RIP3-mediated necroptotic signaling
@en
P2093
Chuangye Yan
Jianping Wu
Xinqi Gong
P3181
P356
10.1016/J.CELREP.2013.08.044
P50
P577
2013-10-17T00:00:00Z