Antiparallel conformation of knob and hole aglycosylated half-antibody homodimers is mediated by a CH2-CH3 hydrophobic interaction

Antiparallel conformation of knob and hole aglycosylated half-antibody homodimers is mediated by a CH2-CH3 hydrophobic interaction

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http://www.wikidata.org/entity/Q27689365
Immunoglobulin Fc Heterodimer Platform Technology: From Design to Applications in Therapeutic Antibodies and ProteinsFc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds.Engineering of Immunoglobulin Fc Heterodimers Using Yeast Surface-Displayed Combinatorial Fc Library ScreeningComputationally Designed Bispecific Antibodies using Negative State Repertoires.Synergistic Neutralization of Pertussis Toxin by a Bispecific Antibody In Vitro and In VivoNew horizons in therapeutic antibody discovery: opportunities and challenges versus small-molecule therapeutics.Structural basis of a novel heterodimeric Fc for bispecific antibody production.Production of bispecific antibodies in "knobs-into-holes" using a cell-free expression systemSingle domain antibody-based bispecific antibody induces potent specific anti-tumor activity.Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies.Improved assembly of bispecific antibodies from knob and hole half-antibodies.Transient and stable CHO expression, purification and characterization of novel hetero-dimeric bispecific IgG antibodies.
P2860

Antiparallel conformation of knob and hole aglycosylated half-antibody homodimers is mediated by a CH2-CH3 hydrophobic interaction

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http://www.wikidata.org/entity/Q27689365
description
2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
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2014年论文
@wuu
name
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@ast
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@en
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@nl
type
label
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@ast
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@en
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@nl
prefLabel
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@ast
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@en
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P921
P3181
P356
P1433
P1476
Antiparallel conformation of k ...... H2-CH3 hydrophobic interaction
@en
P2093
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P921