Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
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Membrane potentials regulating GPCRs: insights from experiments and molecular dynamics simulationsG Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRsEngineering therapeutic antibodies targeting G-protein-coupled receptorsNeurobiological Insights from mGlu Receptor Allosteric Modulation.Structural Studies of G Protein-Coupled ReceptorsThe Effects of Psychological Stress on DepressionPost-expression strategies for structural investigations of membrane proteins.Positive allosteric modulators of metabotropic glutamate 2 receptors in schizophrenia treatmentLarge-scale production and protein engineering of G protein-coupled receptors for structural studiesInvestigation of allosteric modulation mechanism of metabotropic glutamate receptor 1 by molecular dynamics simulations, free energy and weak interaction analysisNovel Structural Approaches to Study GPCR RegulationThe Calcium-Sensing Receptor and the Parathyroid: Past, Present, FutureDisorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasisNovel Allosteric Modulators of G Protein-coupled ReceptorsGeneric GPCR residue numbers - aligning topology maps while minding the gapsStructural insights into ligand recognition and selectivity for classes A, B, and C GPCRsStructure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional ImplicationsmGlu2 Receptor Agonism, but Not Positive Allosteric Modulation, Elicits Rapid Tolerance towards Their Primary Efficacy on Sleep Measures in RatsStructural mechanism of ligand activation in human calcium-sensing receptor.The role of experimental and computational structural approaches in 7TM drug discovery.Vibrational resonance, allostery, and activation in rhodopsin-like G protein-coupled receptors.Label noise in subtype discrimination of class C G protein-coupled receptors: A systematic approach to the analysis of classification errors.2013 Philip S. Portoghese Medicinal Chemistry Lectureship: drug discovery targeting allosteric sites.Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.Molecular Insights into Metabotropic Glutamate Receptor Allosteric ModulationRapid Computational Prediction of Thermostabilizing Mutations for G Protein-Coupled Receptors.Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5.Discovery of GPCR ligands for probing signal transduction pathways.Relationship between in vivo receptor occupancy and efficacy of metabotropic glutamate receptor subtype 5 allosteric modulators with different in vitro binding profilesComputational studies to predict or explain G protein coupled receptor polypharmacologyStructural biology: 'seeing' crystals the XFEL way.Stabilization of G protein-coupled receptors by point mutations.Allosteric Binding Site and Activation Mechanism of Class C G-Protein Coupled Receptors: Metabotropic Glutamate Receptor Family.Structural characterization of triple transmembrane domain containing fragments of a yeast G protein-coupled receptor in an organic : aqueous environment by solution-state NMR spectroscopyIdentification of destabilizing and stabilizing mutations of Ste2p, a G protein-coupled receptor in Saccharomyces cerevisiae.Biosensor-based affinities and binding kinetics of small molecule antagonists to the adenosine A(2A) receptor reconstituted in HDL like particles.A Novel Screening Approach for Optimal and Functional Fusion of T4 Lysozyme in GPCRs.From G Protein-coupled Receptor Structure Resolution to Rational Drug Design.Eukaryotic G protein-coupled receptors as descendants of prokaryotic sodium-translocating rhodopsins.Benchmarking the stability of human detergent-solubilised voltage-gated sodium channels for structural studies using eel as a reference
P2860
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P2860
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@ast
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@en
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@nl
type
label
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@ast
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@en
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@nl
prefLabel
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@ast
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@en
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
@en
P2093
Ali Jazayeri
Andrew S Doré
Giselle R Wiggin
James C Errey
Jayesh C Patel
Kirstie Bennett
Krzysztof Okrasa
Malcolm Weir
Maria Serrano-Vega
P2860
P2888
P304
P3181
P356
10.1038/NATURE13396
P407
P577
2014-07-06T00:00:00Z
P5875
P6179
1029395386