Complete switch from α-2,3- to α-2,6-regioselectivity in Pasteurella dagmatis β-D-galactoside sialyltransferase by active-site redesign
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Advancement of Sialyltransferase Inhibitors: Therapeutic Challenges and OpportunitiesConverting Pasteurella multocidaα2-3-sialyltransferase 1 (PmST1) to a regioselective α2-6-sialyltransferase by saturation mutagenesis and regioselective screening.Glycosyltransferases: mechanisms and applications in natural product development.Glycosyltransferase engineering for carbohydrate synthesis.Enzymatic site-selectivity enabled by structure-guided directed evolution.Active-Site His85 of Pasteurella dagmatis Sialyltransferase Facilitates Productive Sialyl Transfer and So Prevents Futile Hydrolysis of CMP-Neu5Ac.Computer-aided design of human sialyltransferase inhibitors of hST8Sia III.Two N-terminally truncated variants of human β-galactoside α2,6 sialyltransferase I with distinct properties for in vitro protein glycosylation.
P2860
Q30039640-3E994BDB-8F79-49F5-B880-39D6A8EC8427Q36263689-780FF081-EB5E-471C-A2F4-23DEC38F61D3Q38578677-2F88509A-F3AD-498F-882D-054AA31A08C8Q38728088-4D2E1633-02D6-4858-9BBC-17ED7578390EQ39179018-A024E7D2-7A8E-40E8-937F-651674538ACBQ48186491-111C19AA-C0EB-4C5F-BF0B-B4EDE0D5B4F2Q48336629-09D41C17-B3EF-4D4B-94D6-3AA792C984BDQ51361920-BE8C324D-A46E-4334-90BC-992281523ADF
P2860
Complete switch from α-2,3- to α-2,6-regioselectivity in Pasteurella dagmatis β-D-galactoside sialyltransferase by active-site redesign
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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2015 թվականի փետրվարին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Complete switch from α-2,3- to ...... ferase by active-site redesign
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Complete switch from α-2,3- to ...... ferase by active-site redesign
@en
Complete switch from α-2,3- to ...... ferase by active-site redesign
@nl
type
label
Complete switch from α-2,3- to ...... ferase by active-site redesign
@ast
Complete switch from α-2,3- to ...... ferase by active-site redesign
@en
Complete switch from α-2,3- to ...... ferase by active-site redesign
@nl
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Complete switch from α-2,3- to ...... ferase by active-site redesign
@ast
Complete switch from α-2,3- to ...... ferase by active-site redesign
@en
Complete switch from α-2,3- to ...... ferase by active-site redesign
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P2093
P2860
P50
P356
P1476
Complete switch from α-2,3- to ...... ferase by active-site redesign
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P2093
Bernd Nidetzky
Christiane Luley-Goedl
Doris Ribitsch
Hansjörg Weber
P2860
P304
P356
10.1039/C4CC09772F
P407
P577
2015-02-01T00:00:00Z