Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach

Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach

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http://www.wikidata.org/entity/Q27700223
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology.Design, synthesis, and pharmacological evaluation of fluorinated azoles as anti-tubercular agents.Update of Antitubercular Prodrugs from a Molecular Perspective: Mechanisms of Action, Bioactivation Pathways, and Associated Resistance.Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis.Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis.Ultrasound Assisted Synthesis of 4-(Benzyloxy)--(3-chloro-2-(substitutedphenyl)-4-oxoazetidin-1-yl) Benzamide as Challenging Anti-Tubercular ScaffoldInhA, the enoyl-thioester reductase from forms a covalent adduct during catalysis
P2860

Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach

Item
http://www.wikidata.org/entity/Q27700223
description
2015 nî lūn-bûn
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2015 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2015 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
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2015年論文
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2015年論文
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2015年论文
@wuu
name
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@ast
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@en
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@nl
type
label
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@ast
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@en
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@nl
prefLabel
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@ast
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@en
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P921