Discovery of Potent and Selective RSK Inhibitors as Biological Probes

Discovery of Potent and Selective RSK Inhibitors as Biological Probes

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http://www.wikidata.org/entity/Q27701798
MAPK-Activated Protein Kinases (MKs): Novel Insights and ChallengesDevelopment of a RSK Inhibitor as a Novel Therapy for Triple-Negative Breast Cancer.RSK-mediated down-regulation of PDCD4 is required for proliferation, survival, and migration in a model of triple-negative breast cancer.Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the p90 ribosomal S6 kinaseRibosomal S6 kinase (RSK) modulators: a patent review.Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations.Molecular modeling and structure-based drug discovery approach reveals protein kinases as off-targets for novel anticancer drug RH1.Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases.RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1
P2860

Discovery of Potent and Selective RSK Inhibitors as Biological Probes

Item
http://www.wikidata.org/entity/Q27701798
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2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@ast
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@en
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@nl
type
label
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@ast
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@en
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@nl
prefLabel
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@ast
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@en
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P3181
P356
P1433
P1476
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
@en
P2093
P304
P31
P3181
P356
10.1021/ACS.JMEDCHEM.5B00450
P407
P433
P478
P50
P577
P698