Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
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Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugsBeyond immunotherapy: new approaches for disease modifying treatments for early Alzheimer's disease.The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer's disease patients.The chemistry and biology of guanidine natural products.Highlights in BACE1 Inhibitors for Alzheimer's Disease Treatment.
P2860
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
description
2016 nî lūn-bûn
@nan
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@ast
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@en
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@nl
type
label
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@ast
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@en
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@nl
prefLabel
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@ast
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@en
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@nl
P2093
P3181
P1476
Structure-Based Design of an I ...... entral Aβ in Nonhuman Primates
@en
P2093
Alexei Buevich
Andrew W Stamford
Brad Smith
Brian A McKittrick
Diane Grotz
Eric M Parker
Giuseppe Terracina
Guoqing Li
Hongwu Wang
Irina Kazakevich
P304
P3181
P356
10.1021/ACS.JMEDCHEM.5B01995
P407
P577
2016-04-14T00:00:00Z