Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

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http://www.wikidata.org/entity/Q27704291
Structural characterization of nonactive site, TrkA-selective kinase inhibitors.Recent Advances in Targeting ROS1 in Lung Cancer.ALK alterations and inhibition in lung cancer.Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions.Targeting ALK: Precision Medicine Takes on Drug Resistance.Emerging protein kinase inhibitors for treating pancreatic cancer.Tropomyosin receptor kinase inhibitors: an updated patent review for 2010-2016 - Part II.Combating Drug-Resistant Mutants of Anaplastic Lymphoma Kinase with Potent and Selective Type-I1/2 Inhibitors by Stabilizing Unique DFG-Shifted Loop Conformation.Molecular and clinical features of second-generation anaplastic lymphoma kinase inhibitors: ceritinib.Role and targeting of anaplastic lymphoma kinase in cancer.Fusions in solid tumours: diagnostic strategies, targeted therapy, and acquired resistance.A Computational Approach for Prioritizing Selection of Therapies Targeting Drug Resistant Variation in Anaplastic Lymphoma Kinase.Insight into resistance mechanism of anaplastic lymphoma kinase to alectinib and JH-VIII-157-02 caused by G1202R solvent front mutation.Targeting NTRK fusions for the treatment of congenital mesoblastic nephroma.Combining Mutational Signatures, Clonal Fitness, and Drug Affinity to Define Drug-Specific Resistance Mutations in Cancer
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Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

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http://www.wikidata.org/entity/Q27704291
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2016 nî lūn-bûn
@nan
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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label
Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
@en
Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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Discovery of Entrectinib: A Ne ...... r Kinases (Pan-TRKs) inhibitor
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P356
10.1021/ACS.JMEDCHEM.6B00064
P407
P433
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