X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex
about
Identification of direct protein targets of small moleculesInhibition of calcineurin phosphatase activity by a calcineurin B homologous proteinInteraction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motifIdentification and characterization of a conserved family of protein serine/threonine phosphatases homologous to Drosophila retinal degeneration CFKBP12 regulates the localization and processing of amyloid precursor protein in human cell linesTartrate-resistant purple acid phosphatase is synthesized as a latent proenzyme and activated by cysteine proteinasesStructural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexesCrystal structure of human calcineurin complexed with cyclosporin A and human cyclophilinCrystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolutionPost-translational generation of constitutively active cores from larger phosphatases in the malaria parasite, Plasmodium falciparum: implications for proteomicsModulation of Protein-Protein Interactions for the Development of Novel TherapeuticsDirect and Propagated Effects of Small Molecules on Protein-Protein Interaction NetworksCalcineurin inhibition and new-onset diabetes mellitus after transplantationSolution structure of a neurotrophic ligand bound to FKBP12 and its effects on protein dynamicsCrystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1Structural view of a fungal toxin acting on a 14-3-3 regulatory complexThe crystal structure of the novel calcium-binding protein AtCBL2 from Arabidopsis thalianaDesign and structure-based study of new potential FKBP12 inhibitorsCrystal structure of a myristoylated CAP-23/NAP-22 N-terminal domain complexed with Ca2+/calmodulinCrystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA RepairStructure of the Calcineurin-NFAT Complex: Defining a T Cell Activation Switch Using Solution NMR and Crystal CoordinatesStructure of Streptococcus agalactiae serine/threonine phosphataseStructural basis for regulation of protein phosphatase 1 by inhibitor-2Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1)Metal active site elasticity linked to activation of homocysteine in methionine synthasesThe role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphataseSubstrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenesIdentification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactionsStructural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of CalcineurinSolution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulinAnalysing the visible conformational substates of the FK506-binding protein FKBP12High-resolution crystal structure of FKBP12 from Aedes aegyptiStructural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6Structural basis of lenalidomide-induced CK1α degradation by the CRL4(CRBN) ubiquitin ligasevSDC: a method to improve early recognition in virtual screening when limited experimental resources are availableDistinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination.Role of calcineurin and actin dynamics in regulated secretion of microneme proteins in Plasmodium falciparum merozoites during erythrocyte invasion
P2860
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P2860
X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@ast
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@en
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@nl
type
label
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@ast
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@en
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@nl
prefLabel
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@ast
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@en
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@nl
P2093
P3181
P1433
P1476
X-ray structure of calcineurin ...... ppressant FKBP12-FK506 complex
@en
P2093
J A Thomson
J P Griffith
M A Fleming
M D Sintchak
M J Fitzgibbon
P304
P3181
P356
10.1016/0092-8674(95)90439-5
P407
P577
1995-08-11T00:00:00Z