Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design
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Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PDSeveral cooperating binding sites mediate the interaction of a lysosomal enzyme with phosphotransferaseMolecular mechanisms for the conversion of zymogens to active proteolytic enzymesTetrameric dipeptidyl peptidase I directs substrate specificity by use of the residual pro-part domainThe crystal structure of Pseudomonas avirulence protein AvrPphB: A papain-like fold with a distinct substrate-binding siteNatively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray LaserA bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycleStructural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoniCrystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptideThe crystal structure of human cathepsin L complexed with E-64Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPBVery fast empirical prediction and rationalization of protein pKa valuesProbing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates.S1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids.Biochemical characterization of Plasmodium falciparum dipeptidyl aminopeptidase 1Structure and mechanism of cysteine peptidase gingipain K (Kgp), a major virulence factor of Porphyromonas gingivalis in periodontitis.Functional analysis of C1 family cysteine peptidases in the larval gut of Тenebrio molitor and Tribolium castaneum.Enzymatic and Structural Characterization of the Major Endopeptidase in the Venus Flytrap Digestion Fluid.Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.Molecular dynamics studies of caspase-3.Expression and alteration of the S2 subsite of the Leishmania major cathepsin B-like cysteine protease.Cathepsin B carboxydipeptidase specificity analysis using internally quenched fluorescent peptidesStructural determinants of specificity in the cysteine protease cruzain.Crystal structure of human cathepsin S.Interaction of aspartic acid-104 and proline-287 with the active site of m-calpain.Carboxydipeptidase activities of recombinant cysteine peptidases. Cruzain of Trypanosoma cruzi and CPB of Leishmania mexicana.The active-site residue Cys-29 is responsible for the neutral-pH inactivation and the refolding barrier of human cathepsin B.Exploring the interaction of some N-benzyloxycarbonyl-L-phenyl alanyl-L-alanine ketones and bovine spleen cathepsin B by molecular modeling and binding free energy calculation.A Human RNA Viral Cysteine Proteinase That Depends upon a Unique Zn2+-binding Finger Connecting the Two Domains of a Papain-like Fold
P2860
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P2860
Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Crystal structures of recombin ...... ructure-based inhibitor design
@ast
Crystal structures of recombin ...... ructure-based inhibitor design
@en
Crystal structures of recombin ...... ructure-based inhibitor design
@nl
type
label
Crystal structures of recombin ...... ructure-based inhibitor design
@ast
Crystal structures of recombin ...... ructure-based inhibitor design
@en
Crystal structures of recombin ...... ructure-based inhibitor design
@nl
prefLabel
Crystal structures of recombin ...... ructure-based inhibitor design
@ast
Crystal structures of recombin ...... ructure-based inhibitor design
@en
Crystal structures of recombin ...... ructure-based inhibitor design
@nl
P2093
P2860
P356
P1476
Crystal structures of recombin ...... ructure-based inhibitor design
@en
P2093
P2860
P304
P356
10.1074/JBC.270.10.5527
P407
P577
1995-03-10T00:00:00Z