Structure of the RGD protein decorsin: conserved motif and distinct function in leech proteins that affect blood clotting
about
Two independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domainDisintegrins from hematophagous sourcesInherent flexibility in a potent inhibitor of blood coagulation, recombinant nematode anticoagulant protein c2Structure of a conformationally constrained Arg-Gly-Asp sequence inserted into human lysozymeEvaluation of the role of proline residues flanking the RGD motif of dendroaspin, an inhibitior of platelet aggregation and cell adhesionHomology modelling of transferrin-binding protein A from Neisseria meningitidis.A structural tree for proteins containing 3beta-corners.Savignygrin, a platelet aggregation inhibitor from the soft tick Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold.Design of potent beta-lactamase inhibitors by phage display of beta-lactamase inhibitory protein.Theromin, a novel leech thrombin inhibitor.Therostasin, a novel clotting factor Xa inhibitor from the rhynchobdellid leech, Theromyzon tessulatum.Salivary transcriptome of the North American medicinal leech, Macrobdella decora.Enhanced conformational sampling in Monte Carlo simulations of proteins: application to a constrained peptide.Adhesion receptors in health and disease.Platelet aggregation inhibitors from hematophagous animals.Anticoagulants and inhibitors of platelet aggregation derived from leeches.X-ray structure of antistasin at 1.9 A resolution and its modelled complex with blood coagulation factor XaMore than just one: multiplicity of Hirudins and Hirudin-like Factors in the Medicinal Leech, Hirudo medicinalis.Chemical synthesis and structural characterization of the RGD-protein decorsin: a potent inhibitor of platelet aggregation.Engineering Factor Xa Inhibitor with Multiple Platelet-Binding Sites Facilitates its Platelet Targeting.Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor.Toxins in thrombosis and haemostasis: potential beyond imagination.Recombinant decorsin: dynamics of the RGD recognition site.A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: implications for intratypic antigenic variation.Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interactionSystematic replacement of amino acid residues within an Arg-Gly-Asp-containing loop of foot-and-mouth disease virus and effect on cell recognition.Construction of a divalent cell adhesive lysozyme by introducing the Arg-Gly-Asp sequence at two sites.A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin.Mutation of the RGD sequence does not affect plasma membrane association and growth inhibitory effects of elevated IGFBP-2 in vivo.Chloramine T-induced structural and biochemical changes in echistatin.Structural and functional aspects of decorsin and its analog as recognized by integrin αIIbβ3.Medicinal leech therapy-an overall perspective.Substitutions of proline 42 to alanine and methionine 46 to asparagine around the RGD domain of the neurotoxin dendroaspin alter its preferential antagonism to that resembling the disintegrin elegantin.
P2860
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P2860
Structure of the RGD protein decorsin: conserved motif and distinct function in leech proteins that affect blood clotting
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Structure of the RGD protein d ...... ins that affect blood clotting
@ast
Structure of the RGD protein d ...... ins that affect blood clotting
@en
Structure of the RGD protein d ...... ins that affect blood clotting
@nl
type
label
Structure of the RGD protein d ...... ins that affect blood clotting
@ast
Structure of the RGD protein d ...... ins that affect blood clotting
@en
Structure of the RGD protein d ...... ins that affect blood clotting
@nl
prefLabel
Structure of the RGD protein d ...... ins that affect blood clotting
@ast
Structure of the RGD protein d ...... ins that affect blood clotting
@en
Structure of the RGD protein d ...... ins that affect blood clotting
@nl
P2093
P3181
P356
P1433
P1476
Structure of the RGD protein d ...... ins that affect blood clotting
@en
P2093
A M Krezel
J Seymour-Ulmer
R A Lazarus
P304
P3181
P356
10.1126/SCIENCE.8009227
P407
P577
1994-06-24T00:00:00Z