Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms
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Targeting aspartate aminotransferase in breast cancerSubstrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase IIStructural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferaseCrystal structure of Homo sapiens kynureninaseFree energy requirement for domain movement of an enzymeConformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysisCrystal structures of threonine synthase from Thermus thermophilus HB8: conformational change, substrate recognition, and mechanismCrystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognitionCrystal structure of human kynurenine aminotransferase IICrystal Structure of a Homolog of Mammalian Serine Racemase from Schizosaccharomyces pombeStructure, expression, and function of kynurenine aminotransferases in human and rodent brainsStructural Characterization of the Mycobacterium tuberculosis Biotin Biosynthesis Enzymes 7,8-Diaminopelargonic Acid Synthase and Dethiobiotin Synthetase,Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IVMechanism of Inactivation of Escherichia coli Aspartate Aminotransferase by ( S )-4-Amino-4,5-dihydro-2-furancarboxylic Acid,Janus: Prediction and Ranking of Mutations Required for Functional Interconversion of EnzymesCrystal structure and enzymatic properties of a broad substrate-specificity psychrophilic aminotransferase from the Antarctic soil bacterium Psychrobacter sp. B6Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzymeAlternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferaseSubstitution of apolar residues in the active site of aspartate aminotransferase by histidine. Effects on reaction and substrate specificityRedesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residuesHuman mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysisKynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferaseStructure of putrescine aminotransferase from Escherichia coli provides insights into the substrate specificity among class III aminotransferasesCloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidneySerine 254 enhances an induced fit mechanism in murine 5-aminolevulinate synthase.Overexpression, purification, crystallization and structure determination of AspB, a putative aspartate aminotransferase from Mycobacterium tuberculosis.Release of enzyme strain during catalysis reduces the activation energy barrier.Enzyme Tunnels and Gates As Relevant Targets in Drug Design.Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferaseChloroplastic aspartate aminotransferase from Arabidopsis thaliana: an examination of the relationship between the structure of the gene and the spatial structure of the protein.Transient state kinetic investigation of 5-aminolevulinate synthase reaction mechanism.Aspartate aminotransferase: an old dog teaches new tricks.The role of the conserved Lys68*:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: multiple forced covariant amino acid substitutions in natural variants.Aspartate aminotransferase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC 125. Cloning, expression, properties, and molecular modelling.The novel substrate recognition mechanism utilized by aspartate aminotransferase of the extreme thermophile Thermus thermophilus HB8.Directed evolution relieves product inhibition and confers in vivo function to a rationally designed tyrosine aminotransferase.Protein dynamics derived from clusters of crystal structures.Engineering homooligomeric proteins to detect weak intersite allosteric communication: aminotransferases, a case study.Molecular modeling and site-directed mutagenesis reveal essential residues for catalysis in a prokaryote-type aspartate aminotransferase.The use of natural and unnatural amino acid substrates to define the substrate specificity differences of Escherichia coli aspartate and tyrosine aminotransferases.
P2860
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P2860
Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Crystal structures of Escheric ...... and two liganded closed forms
@ast
Crystal structures of Escheric ...... and two liganded closed forms
@en
Crystal structures of Escheric ...... and two liganded closed forms
@nl
type
label
Crystal structures of Escheric ...... and two liganded closed forms
@ast
Crystal structures of Escheric ...... and two liganded closed forms
@en
Crystal structures of Escheric ...... and two liganded closed forms
@nl
prefLabel
Crystal structures of Escheric ...... and two liganded closed forms
@ast
Crystal structures of Escheric ...... and two liganded closed forms
@en
Crystal structures of Escheric ...... and two liganded closed forms
@nl
P2093
P356
P1476
Crystal structures of Escheric ...... and two liganded closed forms
@en
P2093
P304
P356
10.1006/JMBI.1994.1368
P407
P577
1994-06-03T00:00:00Z