High-resolution solution structure of the EGF-like domain of heregulin-alpha
about
Structural analysis of an epidermal growth factor/transforming growth factor-alpha chimera with unique ErbB binding specificitySolution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinitySolution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPaseBinding interaction of the heregulinbeta egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesisSelective formation of ErbB-2/ErbB-3 heterodimers depends on the ErbB-3 affinity of epidermal growth factor-like ligands.Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display.Disulfide bond structure of human epidermal growth factor receptor.Take your partners, please--signal diversification by the erbB family of receptor tyrosine kinases.ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.Biological and conformational evaluation of bifunctional compounds for opioid receptor agonists and neurokinin 1 receptor antagonists possessing two penicillaminesDiscovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies.Deciphering the stepwise binding mode of HRG1β to HER3 by surface plasmon resonance and interaction map.Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3.Improving metabolic stability by glycosylation: bifunctional peptide derivatives that are opioid receptor agonists and neurokinin 1 receptor antagonistsThe importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.Signalling between microvascular endothelium and cardiomyocytes through neuregulin.Endogenous expression of Neuregulin-1 (Nrg1) as a potential modulator of prolactin (PRL) secretion in GH3 cells.The N-terminal domains of neuregulin 1 confer signal attenuation.Analysis of heregulin symmetry by weighted evolutionary tracing.Her2 activation mechanism reflects evolutionary preservation of asymmetric ectodomain dimers in the human EGFR family.HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice.Simulation of homology models for the extracellular domains (ECD) of ErbB3, ErbB4 and the ErbB2-ErbB3 complex in their active conformations.Neuregulin-1 (Nrg1) is mainly expressed in rat pituitary gonadotroph cells and possibly regulates prolactin (PRL) secretion in a juxtacrine manner.
P2860
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P2860
High-resolution solution structure of the EGF-like domain of heregulin-alpha
description
1996 nî lūn-bûn
@nan
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@ast
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@en
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@nl
type
label
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@ast
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@en
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@nl
prefLabel
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@ast
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@en
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@nl
P2093
P356
P1433
P1476
High-resolution solution structure of the EGF-like domain of heregulin-alpha
@en
P2093
M X Sliwkowski
N E Jacobsen
N J Skelton
W J Fairbrother
P304
P356
10.1021/BI952626L
P407
P577
1996-03-19T00:00:00Z