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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

http://www.wikidata.org/entity/Q27734150

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Plant pathogenic RNAs and RNA catalysis Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity Functional identification of catalytic metal ion binding sites within RNA.Understanding nucleic acid-ion interactions Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines.Structure of the ribozyme substrate hairpin of Neurospora VS RNA: a close look at the cleavage site.X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid.A crystallographic study of the binding of 13 metal ions to two related RNA duplexes Solvent Structure and Hammerhead Ribozyme Catalysis Watching DNA polymerase η make a phosphodiester bond Active-Site Monovalent Cations Revealed in a 1.55-Å-Resolution Hammerhead Ribozyme Structure Exploring the role of conformational heterogeneity in cis-autoproteolytic activation of ThnT.Visualizing phosphodiester-bond hydrolysis by an endonuclease Trapping and visualization of a covalent enzyme-phosphate intermediate Crystal structure of 2'-O-Me(CGCGCG)2, an RNA duplex at 1.30 A resolution. Hydration pattern of 2'-O-methylated RNA Chemistry and Biology of Self-Cleaving Ribozymes Tertiary contacts distant from the active site prime a ribozyme for catalysis.Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction Recent advances in the elucidation of the mechanisms of action of ribozymes Computational mutagenesis studies of hammerhead ribozyme catalysis.Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology.Phylogenetic Reconstruction of the Calosphaeriales and Togniniales Using Five Genes and Predicted RNA Secondary Structures of ITS, and Flabellascus tenuirostris gen. et sp. nov Hammerhead redux: does the new structure fit the old biochemical data?Ion-RNA interactions in the RNA pseudoknot of a ribosomal frameshifting site: molecular modeling studies.Caged RNA: photo-control of a ribozyme reaction Empower multiplex cell and tissue-specific CRISPR-mediated gene manipulation with self-cleaving ribozymes and tRNA.The hammerhead ribozyme: structure, catalysis, and gene regulation On the role of magnesium ions in RNA stability.Saccharide-RNA recognition.Ribozymes: the characteristics and properties of catalytic RNAs.Computational approaches toward the design of pools for the in vitro selection of complex aptamers.Identification of the minimal essential RNA sequences responsible for site-specific targeting of the Leishmania RNA virus 1-4 capsid endoribonuclease.Mechanistic consequences of hnRNP C binding to both RNA termini of poliovirus negative-strand RNA intermediates.CHARMM force field parameters for simulation of reactive intermediates in native and thio-substituted ribozymes Existence of efficient divalent metal ion-catalyzed and inefficient divalent metal ion-independent channels in reactions catalyzed by a hammerhead ribozyme Enhanced product stability in the hammerhead ribozyme.4-thio-U cross-linking identifies the active site of the VS ribozyme.New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes Metal ions: supporting actors in the playbook of small ribozymes.Comparison of mode analyses at different resolutions applied to nucleic acid systems.

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P2860

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

http://www.wikidata.org/entity/Q27734150

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1996 nî lūn-bûn

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1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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1996年の論文

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年學術文章

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name

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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SCIENCE.274.5295.2065

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

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P2093

A Klug

http://www.w3.org/2001/XMLSchema#string

B L Stoddard

http://www.w3.org/2001/XMLSchema#string

J B Murray

http://www.w3.org/2001/XMLSchema#string

J R Arnold

http://www.w3.org/2001/XMLSchema#string

W G Scott

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P2860

The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage

Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase

A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

The intervening sequence RNA of Tetrahymena is an enzyme.

The roles of the conserved pyrimidine bases in hammerhead ribozyme catalysis: evidence for a magnesium ion-binding site.

Mixed DNA/RNA polymers are cleaved by the hammerhead ribozyme.

Two autolytic processing reactions of a satellite RNA proceed with inversion of configuration.

Freeze trapping of reaction intermediates.

Ribozymes: structure and mechanism in RNA catalysis.

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2065-9

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scholarly article

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