The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions
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Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundleStructural rearrangement of human lymphotactin, a C chemokine, under physiological solution conditionsIdentification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variantsThe crystal structure of the chemokine domain of fractalkine shows a novel quaternary arrangementThree-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily.Dual GPCR and GAG mimicry by the M3 chemokine decoy receptorStructural and functional studies of the potent anti-HIV chemokine variant P2-RANTESHeterologous quaternary structure of CXCL12 and its relationship to the CC chemokine familyNMR Analysis of the Structure, Dynamics, and Unique Oligomerization Properties of the Chemokine CCL27Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammationMultimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxisOverview of protein structural and functional folds.Overview of protein folds in the immune system.PCalign: a method to quantify physicochemical similarity of protein-protein interfacesChemical modification of a variant of human MIP-1alpha; implications for dimer structureEffects of sulfate position on heparin octasaccharide binding to CCL2 examined by tandem mass spectrometry.Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™Multiple glycosaminoglycan-binding epitopes of monocyte chemoattractant protein-3/CCL7 enable it to function as a non-oligomerizing chemokine.Conditional ablation of astroglial CCL2 suppresses CNS accumulation of M1 macrophages and preserves axons in mice with MOG peptide EAE.Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.Molecular determinants for CC-chemokine recognition by a poxvirus CC-chemokine inhibitorStructural diversity of heparan sulfate binding domains in chemokinesBreast cancer: coordinated regulation of CCL2 secretion by intracellular glycosaminoglycans and chemokine motifs.Molecular basis of lateral force spectroscopy nano-diagnostics: computational unbinding of autism related chemokine MCP-1 from IgG antibodySoluble overexpression and purification of bioactive human CCL2 in E. coli by maltose-binding protein.Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.Homology modeling and molecular dynamics simulations of lymphotactin.NMR in the Analysis of Functional Chemokine Interactions and Drug DiscoveryBotulinum neurotoxin structure, engineering, and novel cellular trafficking and targeting.Monocyte chemoattractant protein-1 (MCP-1): an overviewChemokine oligomerization in cell signaling and migration.Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization.Chemokine oligomerization and interactions with receptors and glycosaminoglycans: the role of structural dynamics in functionIdentification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.A combinatorial approach to biophysically characterise chemokine-glycan binding affinities for drug development.Mechanisms of Regulation of the Chemokine-Receptor Network.The CC-chemokine RANTES increases the attachment of human immunodeficiency virus type 1 to target cells via glycosaminoglycans and also activates a signal transduction pathway that enhances viral infectivity.The CC chemokine eotaxin (CCL11) is a partial agonist of CC chemokine receptor 2b.Lysine 58 and histidine 66 at the C-terminal alpha-helix of monocyte chemoattractant protein-1 are essential for glycosaminoglycan binding.Backbone dynamics of the human CC chemokine eotaxin: fast motions, slow motions, and implications for receptor binding
P2860
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P2860
The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The structure of MCP-1 in two ...... riable quaternary interactions
@ast
The structure of MCP-1 in two ...... riable quaternary interactions
@en
The structure of MCP-1 in two ...... riable quaternary interactions
@nl
type
label
The structure of MCP-1 in two ...... riable quaternary interactions
@ast
The structure of MCP-1 in two ...... riable quaternary interactions
@en
The structure of MCP-1 in two ...... riable quaternary interactions
@nl
prefLabel
The structure of MCP-1 in two ...... riable quaternary interactions
@ast
The structure of MCP-1 in two ...... riable quaternary interactions
@en
The structure of MCP-1 in two ...... riable quaternary interactions
@nl
P2093
P2860
P356
P1476
The structure of MCP-1 in two ...... riable quaternary interactions
@en
P2093
P2860
P356
10.1038/NSB0197-64
P577
1997-01-01T00:00:00Z