Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV
about
Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV proteaseMolecular recognition of cyclic urea HIV-1 protease inhibitorsExpanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1DPC 681 and DPC 684: potent, selective inhibitors of human immunodeficiency virus protease active against clinically relevant mutant variantsThermodynamic linkage between the binding of protons and inhibitors to HIV-1 protease.Inhibition of human endogenous retrovirus-K10 protease in cell-free and cell-based assays.Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy.Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator.Validating the vitality strategy for fighting drug resistance.Carbohydrates in diversity-oriented synthesis: challenges and opportunities.Overcoming drug resistance in HIV-1 chemotherapy: the binding thermodynamics of Amprenavir and TMC-126 to wild-type and drug-resistant mutants of the HIV-1 proteaseLooking at the proteases from a simple perspective.Comparing atom-based with residue-based descriptors in predicting binding site similarity: do backbone atoms matter?DPC 817: a cytidine nucleoside analog with activity against zidovudine- and lamivudine-resistant viral variantsHIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).Effect of Biomolecular Conformation on Docking Simulation: A Case Study on a Potent HIV-1 Protease Inhibitor.Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development.Resistance profiles of cyclic and linear inhibitors of HIV-1 protease.N4-acyl-modified D-2',3'-dideoxy-5-fluorocytidine nucleoside analogues with improved antiviral activity.Pentacycloundecane-diol-based HIV-1 protease inhibitors: biological screening, 2D NMR, and molecular simulation studies.Can cyclic HIV protease inhibitors bind in a non-preferred form? An ab initio, DFT and MM-PB(GB)SA study
P2860
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P2860
Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@ast
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@en
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@nl
type
label
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@ast
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@en
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@nl
prefLabel
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@ast
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@en
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@nl
P2093
P356
P1476
Cyclic urea amides: HIV-1 prot ...... bitor resistant mutants of HIV
@en
P2093
F J Woerner
L T Bacheler
P K Jadhav
S S Garber
P304
P356
10.1021/JM960586T
P407
P577
1997-01-17T00:00:00Z