On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures
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BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currentsMechanisms of maurotoxin action on Shaker potassium channels.Immune responses in hookworm infectionsPotassium channel modulation by a toxin domain in matrix metalloprotease 23Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channelsSolution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratusChemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxinsComputational Studies of Venom Peptides Targeting Potassium ChannelsSea anemone (Cnidaria, Anthozoa, Actiniaria) toxins: an overviewRefined solution structure of omega-conotoxin GVIA: implications for calcium channel bindingStructural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: Solution structure of the potassium channel inhibitor HsTX1kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivityNew binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxinStructures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels: implications for movement of the C-terminal cysteine-rich domainNew Tricks of an Old Pattern: STRUCTURAL VERSATILITY OF SCORPION TOXINS WITH COMMON CYSTEINE SPACINGKv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseasesStructural basis for antimicrobial activity of lasiocepsinModeling the structure of agitoxin in complex with the Shaker K+ channel: a computational approach based on experimental distance restraints extracted from thermodynamic mutant cyclesThe D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferationThe venomous cocktail of the vampire snail Colubraria reticulata (Mollusca, Gastropoda)The Mediterranean scorpion Mesobuthus gibbosus (Scorpiones, Buthidae): transcriptome analysis and organization of the genome encoding chlorotoxin-like peptidesStructural and functional characterization of ryanodine receptor-natrin toxin interactionKalium: a database of potassium channel toxins from scorpion venom.Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom.A family of secreted mucins from the parasitic nematode Toxocara canis bears diverse mucin domains but shares similar flanking six-cysteine repeat motifs.Structure of conkunitzin-S1, a neurotoxin and Kunitz-fold disulfide variant from cone snailGenomic structure of a potassium channel toxin from Heteractis magnifica.Two new 4-Cys conotoxins (framework 14) of the vermivorous snail Conus austini from the Gulf of Mexico with activity in the central nervous system of mice.Bioinformatic characterizations and prediction of K+ and Na+ ion channels effector toxins.Helminth Immunomodulation in Autoimmune Disease.Molecular diversity and functional evolution of scorpion potassium channel toxinsMapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity.Innate immune responses of a scleractinian coral to vibriosis.Structural basis for the biological activity of dendrotoxin-I, a potent potassium channel blocker.Molecular diversity of the telson and venom components from Pandinus cavimanus (Scorpionidae Latreille 1802): transcriptome, venomics and function.Structure of the BgK-Kv1.1 complex based on distance restraints identified by double mutant cycles. Molecular basis for convergent evolution of Kv1 channel blockers.Inhibition of single Shaker K channels by kappa-conotoxin-PVIIARaalin, a transcript enriched in the honey bee brain, is a remnant of genomic rearrangement in Hymenoptera.Evidence for a function-specific mutation in the neurotoxin, parabutoxin 3.
P2860
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P2860
On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
On the convergent evolution of ...... xins with unrelated structures
@ast
On the convergent evolution of ...... xins with unrelated structures
@en
On the convergent evolution of ...... xins with unrelated structures
@nl
type
label
On the convergent evolution of ...... xins with unrelated structures
@ast
On the convergent evolution of ...... xins with unrelated structures
@en
On the convergent evolution of ...... xins with unrelated structures
@nl
prefLabel
On the convergent evolution of ...... xins with unrelated structures
@ast
On the convergent evolution of ...... xins with unrelated structures
@en
On the convergent evolution of ...... xins with unrelated structures
@nl
P2093
P50
P3181
P356
P1476
On the convergent evolution of ...... xins with unrelated structures
@en
P2093
A L Harvey
C L de Medeiros
M Dauplais
P304
P3181
P356
10.1074/JBC.272.7.4302
P407
P577
1997-02-01T00:00:00Z