Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy
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Purification, cDNA cloning, and expression of a new human blood plasma glutamate carboxypeptidase homologous to N-acetyl-aspartyl-alpha-glutamate carboxypeptidase/prostate-specific membrane antigenThe genome sequence of the extreme thermophile Thermus thermophilusCrystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation.Glucarpidase to combat toxic levels of methotrexate in patientsHuman glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active siteCarnosinases, their substrates and diseasesStructure of peptidase T from Salmonella typhimuriumCrystal structure of bacterial multidrug efflux transporter AcrBEssential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 familyYeast beta-alanine synthase shares a structural scaffold and origin with dizinc-dependent exopeptidasesCrystal structure of a hypothetical protein, TT1725, from Thermus thermophilus HB8 at 1.7 A resolutionCrystal structures of yeast beta-alanine synthase complexes reveal the mode of substrate binding and large scale domain closure movementsX-ray structure of ILL2, an auxin-conjugate amidohydrolase fromArabidopsis thalianaStructural basis for substrate recognition and hydrolysis by mouse carnosinase CN2Structural Basis for Catalysis by the Mono- and Dimetalated Forms of the dapE-Encoded N-succinyl-l,l-Diaminopimelic Acid DesuccinylaseCrystal Structure of Staphylococcus aureus Metallopeptidase (Sapep) Reveals Large Domain Motions between the Manganese-bound and Apo-statesCrystal Structure and Mutational Analysis of Aminoacylhistidine Dipeptidase from Vibrio alginolyticus Reveal a New Architecture of M20 MetallopeptidasesStructural and Functional Analyses Reveal That Staphylococcus aureus Antibiotic Resistance Factor HmrA Is a Zinc-dependent EndopeptidaseMutational and Structural Analysis of L-N-Carbamoylase Reveals New Insights into a Peptidase M20/M25/M40 Family MemberStructure of an amidohydrolase, SACOL0085, from methicillin-resistantStaphylococcus aureusCOLInsights into Substrate Specificity and Metal Activation of Mammalian Tetrahedral Aspartyl AminopeptidaseStructure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase familyThe dimerization domain in DapE enzymes is required for catalysisEnzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitutionMutational analysis of aspartoacylase: implications for Canavan diseaseSequence identification and characterization of human carnosinase and a closely related non-specific dipeptidaseDetermination of Carboxypeptidase Activity in Clinical Pathogens by Gas Chromatography-Mass SpectrometryPurification and characterization of a cobalt-activated carboxypeptidase from the hyperthermophilic archaeon Pyrococcus furiosus.Expression, purification, crystallization and preliminary X-ray crystallographic studies of a novel acetylcitrulline deacetylase from Xanthomonas campestris.Purification and characterization of the folate catabolic enzyme p-aminobenzoyl-glutamate hydrolase from Escherichia coli.3D structure of Sulfolobus solfataricus carboxypeptidase developed by molecular modeling is confirmed by site-directed mutagenesis and small angle X-ray scatteringAminoacylase I deficiency due to ACY1 mRNA exon skipping.Bacterial protease inhibitors.Identification of a Histidine Metal Ligand in the argE-Encoded N-Acetyl-L-Ornithine Deacetylase from Escherichia coliStructure and computational analysis of a novel protein with metallopeptidase-like and circularly permuted winged-helix-turn-helix domains reveals a possible role in modified polysaccharide biosynthesisInhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.Structural characterization of Zn(II)-, Co(II)-, and Mn(II)-loaded forms of the argE-encoded N-acetyl-L-ornithine deacetylase from Escherichia coliCase files of the New York City Poison Control Center: antidotal strategies for the management of methotrexate toxicity.Characterization of a thermostable L-arabinose (D-galactose) isomerase from the hyperthermophilic eubacterium Thermotoga maritima.Purification, crystallization and preliminary X-ray analysis of an aminoacylhistidine dipeptidase (PepD) from Vibrio alginolyticus.
P2860
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P2860
Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Crystal structure of carboxype ...... applications in cancer therapy
@ast
Crystal structure of carboxype ...... applications in cancer therapy
@en
Crystal structure of carboxype ...... applications in cancer therapy
@nl
type
label
Crystal structure of carboxype ...... applications in cancer therapy
@ast
Crystal structure of carboxype ...... applications in cancer therapy
@en
Crystal structure of carboxype ...... applications in cancer therapy
@nl
prefLabel
Crystal structure of carboxype ...... applications in cancer therapy
@ast
Crystal structure of carboxype ...... applications in cancer therapy
@en
Crystal structure of carboxype ...... applications in cancer therapy
@nl
P2093
P3181
P1433
P1476
Crystal structure of carboxype ...... applications in cancer therapy
@en
P2093
P304
P3181
P356
10.1016/S0969-2126(97)00191-3
P577
1997-03-15T00:00:00Z