The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control
about
Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblastsGenomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shapeInsight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexesRestricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITFIntermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNAStructures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targetsCrystal Structure of the Minimalist Max-E47 Protein ChimeraThe basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNAThe circadian E-box: when perfect is not good enough.Interactions between the Su(Hw) and Mod(mdg4) proteins required for gypsy insulator function.Correlations among amino acid sites in bHLH protein domains: an information theoretic analysis.Max-E47, a designed minimalist protein that targets the E-box DNA site in vivo and in vitro.Cha, a basic helix-loop-helix transcription factor involved in the regulation of upstream stimulatory factor activity.Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif.Hybrids of the bHLH and bZIP protein motifs display different DNA-binding activities in vivo vs. in vitro.Small molecule inhibitors of Myc/Max dimerization and Myc-induced cell transformation.Reengineering natural design by rational design and in vivo library selection: the HLH subdomain in bHLHZ proteins is a unique requirement for DNA-binding functionThe basic domain of ATH5 mediates neuron-specific promoter activity during retina development.The Mad and Myc basic domains are functionally equivalent.Convergent evolution of gene networks by single-gene duplications in higher eukaryotes.Accurate discrimination of bHLH domains in plants, animals, and fungi using biologically meaningful sites.Molecular characterization and functions of fatty acid and retinoid binding protein gene (Ab-far-1) in Aphelenchoides besseyi.Structural biology of bacterial multidrug resistance gene regulators.Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants.Evolution of the Max and Mlx networks in animals.Quantitative modeling of transcription factor binding specificities using DNA shape.MtbHLH1, a bHLH transcription factor involved in Medicago truncatula nodule vascular patterning and nodule to plant metabolic exchanges.Phylogenetic analysis and classification of the fungal bHLH domain.Evolutionary and comparative analysis of MYB and bHLH plant transcription factors.DNA binding of Myc/Max/Mad network complexes to oligonucleotides containing two E box elements: c-Myc/Max heterodimers do not bind DNA cooperatively.Genome-wide analysis of basic helix-loop-helix (bHLH) transcription factors in Brachypodium distachyon.Establishment of distinct MyoD, E2A, and twist DNA binding specificities by different basic region-DNA conformations.Identifying DNA-binding proteins using structural motifs and the electrostatic potential.Novel CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells.Visualization of Myc/Max/Mad family dimers and the competition for dimerization in living cells.Functional properties of an alternative, tissue-specific promoter for rice NADPH-dependent dihydroflavonol reductaseAn atypical bHLH protein encoded by POSITIVE REGULATOR OF GRAIN LENGTH 2 is involved in controlling grain length and weight of rice through interaction with a typical bHLH protein APG.Calcium-dependent binding of Myc to calmodulin.Max is acetylated by p300 at several nuclear localization residuesAsn(78) and His(81) form a destabilizing locus within the Max HLH-LZ homodimer.
P2860
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P2860
The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The crystal structure of an in ...... sms of transcriptional control
@ast
The crystal structure of an in ...... sms of transcriptional control
@en
The crystal structure of an in ...... sms of transcriptional control
@nl
type
label
The crystal structure of an in ...... sms of transcriptional control
@ast
The crystal structure of an in ...... sms of transcriptional control
@en
The crystal structure of an in ...... sms of transcriptional control
@nl
prefLabel
The crystal structure of an in ...... sms of transcriptional control
@ast
The crystal structure of an in ...... sms of transcriptional control
@en
The crystal structure of an in ...... sms of transcriptional control
@nl
P2093
P1433
P1476
The crystal structure of an in ...... sms of transcriptional control
@en
P2093
P Brownlie
P304
P356
10.1016/S0969-2126(97)00207-4
P407
P577
1997-04-15T00:00:00Z