Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
about
Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteinsCD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding siteAnaplastic lymphoma kinase: signalling in development and diseaseMutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeatCa2+ binding to complement-type repeat domains 5 and 6 from the low-density lipoprotein receptor-related proteinOrchestration of secretory protein folding by ER chaperonesNMR solution structure of complement-like repeat CR8 from the low density lipoprotein receptor-related proteinNMR solution structure of complement-like repeat CR3 from the low density lipoprotein receptor-related protein. Evidence for specific binding to the receptor binding domain of human alpha(2)-macroglobulinNMR structure of a concatemer of the first and second ligand-binding modules of the human low-density lipoprotein receptorThree-dimensional NMR structure of the sixth ligand-binding module of the human LDL receptor: comparison of two adjacent modules with different ligand binding specificitiesStructure of a rat α1-macroglobulin receptor-binding domain dimerCatalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinaseThe solution structure of the viral binding domain of Tva, the cellular receptor for subgroup A avian leukosis and sarcoma virusSolution structure of the viral receptor domain of Tva and its implications in viral entryStructure of the Minimal Interface Between ApoE and LRPThe Structure, Dynamics, and Binding of the LA45 Module Pair of the Low-Density Lipoprotein Receptor Suggest an Important Role for LA4 in Ligand ReleaseGentamicin Binds to the Megalin Receptor as a Competitive Inhibitor Using the Common Ligand Binding Motif of Complement Type Repeats: INSIGHT FROM THE NMR STRUCTURE OF THE 10TH COMPLEMENT TYPE REPEAT DOMAIN ALONE AND IN COMPLEX WITH GENTAMICINAtomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tailLRP5 and LRP6 in development and diseaseThe closed conformation of the LDL receptor is destabilized by the low Ca(++) concentration but favored by the high Mg(++) concentration in the endosomeThe activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitorThe human LGR7 low-density lipoprotein class A module requires calcium for structureGenetic, molecular and functional analyses of complement factor I deficiencyIdentification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivoAnalysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related proteinRoles of functional and structural domains of hepatocyte growth factor activator inhibitor type 1 in the inhibition of matriptaseStructural basis of transcobalamin recognition by human CD320 receptorThe relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation.Switch region for pathogenic structural change in conformational disease and its predictionDecoding of lipoprotein-receptor interactions: properties of ligand binding modules governing interactions with apolipoprotein E.The single ligand-binding repeat of Tva, a low density lipoprotein receptor-related protein, contains two ligand-binding surfaces.Receptor-induced conformational changes in the SU subunit of the avian sarcoma/leukosis virus A envelope protein: implications for fusion activation.The spacing between cysteines two and three of the LDL-A module of Tva is important for subgroup A avian sarcoma and leukosis virus entryNovel low density lipoprotein receptor variant linked to early onset acute myocardial infarction in a patient with familial hypercholesterolaemia.Production and characterization of a soluble, active form of Tva, the subgroup A avian sarcoma and leukosis virus receptorLipoprotein receptors: new roles for ancient proteins.Characterization of determinants for envelope binding and infection in tva, the subgroup A avian sarcoma and leukosis virus receptorCorin mutations K317E and S472G from preeclamptic patients alter zymogen activation and cell surface targeting. [Corrected]The minor receptor group of human rhinovirus (HRV) includes HRV23 and HRV25, but the presence of a lysine in the VP1 HI loop is not sufficient for receptor binding
P2860
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P2860
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@ast
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@en
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@nl
type
label
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@ast
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@en
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@nl
prefLabel
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@ast
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@en
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@nl
P2093
P3181
P356
P1433
P1476
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
@en
P2093
P2888
P3181
P356
10.1038/41798
P407
P577
1997-08-14T00:00:00Z
P5875
P6179
1005129508