High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA
about
A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding.Synthesis and evaluation of a series of C5'-substituted duocarmycin SA analogs.Modeling anticancer drug-DNA interactions via mixed QM/MM molecular dynamics simulations.Structural influence of indole C5-N-substitutents on the cytotoxicity of seco-duocarmycin analogs.Sliding of alkylating anticancer drugs along the minor groove of DNA: new insights on sequence selectivityInvestigation of the transformations of a novel anti-cancer agent combining HPLC, HPLC-MS and direct ESI-HRMS analyses.NMR structure of the (+)-CPI-indole/d(GACTAATTGAC)-d(GTCAATTAGTC) covalent complex.The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry-Biology Interface.Toxicity and repair of DNA adducts produced by the natural product yatakemycin.
P2860
Q30661435-72D01BAA-3FDE-49BE-86EE-7A0C603A9931Q33840901-F472994E-FCA9-4276-A8F5-A724FDE12FE3Q36514784-F21CB441-21E0-4B88-84D5-AE7E685E673DQ39547215-6FB8A284-393B-4338-8550-D74EFBD73F23Q41845099-61F7697C-8787-40B2-BE1D-625061443982Q42215830-7B94CB3C-88C0-4890-8BED-892FF0189319Q44652399-14D9278D-83C8-4E1E-B319-3158CF40CCBFQ46236467-1434DF99-2B05-4DF2-823E-3CBCBC07F725Q48320685-E24A6D52-D67A-4D5B-9848-E668737ED463
P2860
High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
High resolution solution struc ...... antitumor agent duocarmycin SA
@ast
High resolution solution struc ...... antitumor agent duocarmycin SA
@en
High resolution solution struc ...... antitumor agent duocarmycin SA
@nl
type
label
High resolution solution struc ...... antitumor agent duocarmycin SA
@ast
High resolution solution struc ...... antitumor agent duocarmycin SA
@en
High resolution solution struc ...... antitumor agent duocarmycin SA
@nl
prefLabel
High resolution solution struc ...... antitumor agent duocarmycin SA
@ast
High resolution solution struc ...... antitumor agent duocarmycin SA
@en
High resolution solution struc ...... antitumor agent duocarmycin SA
@nl
P2093
P356
P1476
High resolution solution struc ...... antitumor agent duocarmycin SA
@en
P2093
P304
P356
10.1006/JMBI.1997.1223
P407
P577
1997-09-19T00:00:00Z