The high resolution crystal structure of deoxyhemoglobin S
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Crystal structure of deoxy-human hemoglobin beta6 Glu --> Trp. Implications for the structure and formation of the sickle cell fiberThe structural and functional analysis of the hemoglobin D component from chickenInternal Binding of Halogenated Phenols in Dehaloperoxidase-Hemoglobin Inhibits Peroxidase FunctionThree-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNaseAryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of HemoglobinSolubility of fluoromethemoglobin S: effect of phosphate and temperature on polymerization.Wetting of nonconserved residue-backbones: A feature indicative of aggregation associated regions of proteins.Heterogeneous nucleation in sickle hemoglobin: experimental validation of a structural mechanism.Dynamic reorganization of metabolic enzymes into intracellular bodiesA human embryonic hemoglobin inhibits Hb S polymerization in vitro and restores a normal phenotype to mouse models of sickle cell disease.Heterogeneous nucleation and crowding in sickle hemoglobin: an analytic approach.Sickle Cell Hemoglobin with Mutation at αHis-50 Has Improved Solubility.Inhibition of hemoglobin S polymerization in vitro by a novel 15-mer EF-helix beta73 histidine-containing peptide.Probing the Twisted Structure of Sickle Hemoglobin Fibers via Particle Simulations.Relationship between beta4 hydrogen bond and beta6 hydrophobic interactions during aggregate, fiber or crystal formation in oversaturated solutions of hemoglobin A and SDesign of therapeutic proteins with enhanced stability.Mapping polymerization and allostery of hemoglobin S using point mutations.Protein/Peptide Aggregation and Amyloidosis on Biointerfaces.Structures and oxygen affinities of crystalline human hemoglobin C (β6 Glu->Lys) in the R and R2 quaternary structuresProtein function in precision medicine: deep understanding with machine learning.A tractable genotype-phenotype map modelling the self-assembly of protein quaternary structure.Structural basis for the antipolymer activity of Hb ζ2β(s)2 trapped in a tense conformation.Crystal structure of carbonmonoxy sickle hemoglobin in R-state conformation.Visualizing red blood cell sickling and the effects of inhibition of sphingosine kinase 1 using soft X-ray tomography.NMR study of the cataract-linked P23T mutant of human gammaD-crystallin shows minor changes in hydrophobic patches that reflect its retrograde solubility.Role of partial protein unfolding in alcohol-induced protein aggregation.A model for the sickle hemoglobin fiber using both mutation sitesCharacterization of the impact of alternative splicing on protein dynamics: the cases of glutathione S-transferase and ectodysplasin-A isoforms.Beta7E-beta132K salt bridge and sickle haemoglobin stability and conformation.Linkage of interactions in sickle hemoglobin fiber assembly: inhibitory effect emanating from mutations in the AB region of the alpha-chain is annulled by a mutation at its EF corner.Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.Influence of semisynthetic modification of the scaffold of a contact domain of HbS on polymerization: role of flexible surface topology in polymerization inhibition.Normal and abnormal protein subunit interactions in hemoglobins.Simple model of sickle hemogloblin.Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.The genetic basis and evolution of red blood cell sickling in deer.Atomic insights into the genesis of cellular filaments by globular proteinsSynergistic Integration of Laboratory and Numerical Approaches in Studies of the Biomechanics of Diseased Red Blood Cells
P2860
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P2860
The high resolution crystal structure of deoxyhemoglobin S
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
The high resolution crystal structure of deoxyhemoglobin S
@ast
The high resolution crystal structure of deoxyhemoglobin S
@en
The high resolution crystal structure of deoxyhemoglobin S
@nl
type
label
The high resolution crystal structure of deoxyhemoglobin S
@ast
The high resolution crystal structure of deoxyhemoglobin S
@en
The high resolution crystal structure of deoxyhemoglobin S
@nl
prefLabel
The high resolution crystal structure of deoxyhemoglobin S
@ast
The high resolution crystal structure of deoxyhemoglobin S
@en
The high resolution crystal structure of deoxyhemoglobin S
@nl
P2093
P356
P1476
The high resolution crystal structure of deoxyhemoglobin S
@en
P2093
D J Harrington
P304
P356
10.1006/JMBI.1997.1253
P407
P577
1997-09-26T00:00:00Z