Structure of the cyclin-dependent kinase inhibitor p19Ink4d
about
INK4 cell cycle inhibitors direct transcriptional inactivation of NF-kappaBThe telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongationTumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR dataStructure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activityStructure and stability of the ankyrin domain of the Drosophila Notch receptorCrystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutationsIkappa Balpha functions through direct contacts with the nuclear localization signals and the DNA binding sequences of NF-kappaBCloning and identification of MYPT3: a prenylatable myosin targetting subunit of protein phosphatase 1Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information.Conservation of glp-1 regulation and function in nematodes.Structural determinants present in the C-terminal binding protein binding site of adenovirus early region 1A proteins.Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution.Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.Protein-protein interactions in receptor activation and intracellular signalling.Structure and mechanism in NF-kappa B/I kappa B signaling.Selectivity and potency of cyclin-dependent kinase inhibitors.Mechanisms by which IkappaB proteins control NF-kappaB activity.Utilizing NMR to study the structure of growth-inhibitory proteins.The therapeutic potential of targeting the cell cycle.Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes.Tally: a scoring tool for boundary determination between repetitive and non-repetitive protein sequences.The myxoma virus m-t5 ankyrin repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cellsFunctional dynamics of the folded ankyrin repeats of I kappa B alpha revealed by nuclear magnetic resonanceGenomic organization, differential expression, and interaction of SQUAMOSA promoter-binding-like transcription factors and microRNA156 in rice.Comparative structure and characterization of a CDKN2 gene in a Xiphophorus fish melanoma model.Structural insights into the functional diversity of the CDK-cyclin family
P2860
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P2860
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@ast
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@en
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@nl
type
label
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@ast
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@en
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@nl
prefLabel
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@ast
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@en
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@nl
P2093
P2860
P356
P1433
P1476
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
@en
P2093
D H Brotherton
L Brizuela
P J Domaille
S J Archer
S L Brenner
P2860
P2888
P304
P356
10.1038/40202
P407
P577
1997-10-30T00:00:00Z
P6179
1038527164