The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex
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Crystal structure of the calcium-stabilized human factor IX Gla domain bound to a conformation-specific anti-factor IX antibodyInhibition of acute vascular thrombosis in chimpanzees by an anti-human tissue factor antibody targeting the factor X binding siteComplex of a Protective Antibody with Its Ebola Virus GP Peptide Epitope: Unusual Features of a Vλx Light ChainStructure of an Fab–Protease Complex Reveals a Highly Specific Non-canonical Mechanism of InhibitionCrystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanismCrystal Structure of the Engineered Neutralizing Antibody M18 Complexed to Domain 4 of the Anthrax Protective AntigenA Reverse Binding Motif That Contributes to Specific Protease Inhibition by AntibodiesA network-based multi-target computational estimation scheme for anticoagulant activities of compoundsHigh-Resolution NMR Studies of Human Tissue FactorMultiple diverse ligands binding at a single protein site: a matter of pre-existing populations.PEPOP: computational design of immunogenic peptides.Folding funnels and binding mechanisms.Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.An allosteric anti-hepsin antibody derived from a constrained phage display library.Detection of tissue factor antigen and coagulation activity in coronary artery thrombi isolated from patients with ST-segment elevation acute myocardial infarction.Disulfide isomerization switches tissue factor from coagulation to cell signalingCoarse-grained models for simulations of multiprotein complexes: application to ubiquitin binding.Structure-Function Relationship of the Interaction between Tissue Factor and Factor VIIa.Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndromeCross-talk of integrin alpha3beta1 and tissue factor in cell migration.Structural and mechanistic insight into how antibodies inhibit serine proteases.Tissue factor-bearing microparticles and thrombus formation.Tissue factor and cell signalling in cancer progression and thrombosis.Structural biology of factor VIIa/tissue factor initiated coagulationProtein anticoagulants targeting factor VIIa-tissue factor complex: a comprehensive review.Tissue factor non-coagulant signaling - molecular mechanisms and biological consequences with a focus on cell migration and apoptosis.The N-terminal epidermal growth factor-like domain of coagulation factor IX. Probing its functions in the activation of factor IX and factor X with a monoclonal antibody.SAbDab: the structural antibody database.SKEMPI: a Structural Kinetic and Energetic database of Mutant Protein Interactions and its use in empirical models.A Machine Learning Approach for Hot-Spot Detection at Protein-Protein Interfaces.Macromolecular substrate affinity for the tissue factor-factor VIIa complex is independent of scissile bond docking.Glycosylation of tissue factor is not essential for its transport or functions.Hinge bending within the cytokine receptor superfamily revealed by the 2.4 A crystal structure of the extracellular domain of rabbit tissue factor.Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity.High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa.A structural mechanism of flavonoids in inhibiting serine proteases.Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody.
P2860
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P2860
The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@ast
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@en
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@nl
type
label
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@ast
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@en
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@nl
prefLabel
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@ast
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@en
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@nl
P2093
P3181
P356
P1476
The mechanism of an inhibitory ...... tor, Fab 5G9 and TF.G9 complex
@en
P2093
P304
P3181
P356
10.1006/JMBI.1997.1512
P407
P577
1998-02-01T00:00:00Z