Crystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1-A resolution
about
Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteinsIdentification of the yqhE and yafB genes encoding two 2, 5-diketo-D-gluconate reductases in Escherichia coliVitamin C inhibits the enzymatic activity of Streptococcus pneumoniae hyaluronate lyaseThe crystal structure of rat liver AKR7A1. A dimeric member of the aldo-keto reductase superfamilyAlternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factorStructural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductaseGenetic and biochemical characterization of the pathway in Pantoea citrea leading to pink disease of pineappleMolecular modeling of substrate binding in wild-type and mutant Corynebacteria 2,5-diketo-D-gluconate reductases.DNA from uncultured organisms as a source of 2,5-diketo-D-gluconic acid reductasesProduction and characterization of a thermostable alcohol dehydrogenase that belongs to the aldo-keto reductase superfamily.Co-factor binding confers substrate specificity to xylose reductase from Debaryomyces hansenii.C-Terminal region of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates.Binding of pyridine nucleotide coenzymes to the beta-subunit of the voltage-sensitive K+ channel.Identification of a novel NADH-specific aldo-keto reductase using sequence and structural homologies.The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.Kinetic alteration of a human dihydrodiol/3alpha-hydroxysteroid dehydrogenase isoenzyme, AKR1C4, by replacement of histidine-216 with tyrosine or phenylalanine.Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen.Alteration of the specificity of the cofactor-binding pocket of Corynebacterium 2,5-diketo-D-gluconic acid reductase A.Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+.Structural and mutational analysis of Trypanosoma brucei prostaglandin H2 reductase provides insight into the catalytic mechanism of aldo-ketoreductases.
P2860
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P2860
Crystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1-A resolution
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@ast
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@en
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@nl
type
label
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@ast
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@en
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@nl
prefLabel
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@ast
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@en
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@nl
P2093
P2860
P356
P1476
Crystal structure of 2,5-diket ...... with NADPH at 2.1-A resolution
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.12.6768
P407
P577
1998-06-09T00:00:00Z