Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
about
Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor XaStructure of tick anticoagulant peptide at 1.6 A resolution complexed with bovine pancreatic trypsin inhibitorSolution structure of a Kunitz-type chymotrypsin inhibitor isolated from the elapid snake Bungarus fasciatusIsolation, Cloning and Structural Characterisation of Boophilin, a Multifunctional Kunitz-Type Proteinase Inhibitor from the Cattle TickCrystal structure of the prothrombinase complex from the venom of Pseudonaja textilisStructural basis for dual inhibitory role of tamarind Kunitz inhibitor (TKI) against factor Xa and trypsinCharacterization of anti-hemostatic factors in the argasid, Argas monolakensis: implications for the evolution of blood-feeding in the soft tick familyRole of zymogen and activated factor X as scaffolds for the inhibition of the blood coagulation factor VIIa-tissue factor complex by recombinant nematode anticoagulant protein c2.Functional and structural characterization of factor Xa dimer in solution.Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin.The many faces of protease-protein inhibitor interactionThe structure of thrombin, a chameleon-like proteinase.Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivoFactor Xa active site substrate specificity with substrate phage display and computational molecular modeling.Factor Va alters the conformation of the Na+-binding loop of factor Xa in the prothrombinase complexToxins in thrombosis and haemostasis: potential beyond imagination.The conformational switch from the factor X zymogen to protease state mediates exosite expression and prothrombinase assembly.The critical role of the 185-189-loop in the factor Xa interaction with Na+ and factor Va in the prothrombinase complex.Engineered factor Xa variants retain procoagulant activity independent of direct factor Xa inhibitors.Structural and docking studies of potent ethionamide boosters.Evolution of hematophagy in ticks: common origins for blood coagulation and platelet aggregation inhibitors from soft ticks of the genus Ornithodoros.Localization of an antithrombin exosite that promotes rapid inhibition of factors Xa and IXa dependent on heparin activation of the serpin.Incorporation of factor Va into prothrombinase is required for coordinated cleavage of prothrombin by factor Xa.
P2860
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P2860
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
description
1998 nî lūn-bûn
@nan
1998 թուականին հրատարակուած գիտական յօդուած
@hyw
1998 թվականին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@ast
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@en
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@nl
type
label
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@ast
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@en
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@nl
prefLabel
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@ast
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@en
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@nl
P2093
P356
P1476
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
@en
P2093
P304
P356
10.1006/JMBI.1998.2069
P407
P577
1998-01-01T00:00:00Z