TERT promoter mutations in primary and secondary glioblastomas. - Wikidata - wikimedia - TriplyDB

TERT promoter mutations in primary and secondary glioblastomas.

TERT promoter mutations in primary and secondary glioblastomas.

http://www.wikidata.org/entity/Q27852506

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Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical Implications Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene CIViC database The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma Epidemiologic and molecular prognostic review of glioblastoma TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples samples.Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas.Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma.RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas.Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations.Recurrent 12q13-15 chromosomal aberrations, high frequency of isocitrate dehydrogenase 1 mutations, and absence of high mobility group AT-hook 2 expression in periosteal chondromas.TERT promoter mutations and telomere length in adult malignant gliomas and recurrences.A wide spectrum of EGFR mutations in glioblastoma is detected by a single clinical oncology targeted next-generation sequencing panel A somatic reference standard for cancer genome sequencing.Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis Combination genetic signature stratifies lower-grade gliomas better than histological grade.TERT promoter mutations contribute to IDH mutations in predicting differential responses to adjuvant therapies in WHO grade II and III diffuse gliomas.Biomarker-based prognostic stratification of young adult glioblastoma Rapid Intraoperative Molecular Characterization of Glioma.TERT promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.ADAM9 Expression Is Associate with Glioma Tumor Grade and Histological Type, and Acts as a Prognostic Factor in Lower-Grade Gliomas TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.Clinicopathological characteristics of TERT promoter mutation and telomere length in hepatocellular carcinoma Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.Prognostic and predictive biomarkers in adult and pediatric gliomas: toward personalized treatment.Telomerase promoter mutations in cancer: an emerging molecular biomarker?Genomic discoveries in adult astrocytoma Genetics and immunotherapy: using the genetic landscape of gliomas to inform management strategies.Diagnostic, prognostic and predictive relevance of molecular markers in gliomas.Novel chemotherapeutics and other therapies for treating high-grade glioma.Evolving Molecular Genetics of Glioblastoma.Understanding TERT Promoter Mutations: A Common Path to Immortality.Elucidating the cancer-specific genetic alteration spectrum of glioblastoma derived cell lines from whole exome and RNA sequencing.Altered TERT promoter and other genomic regulatory elements: occurrence and impact.

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TERT promoter mutations in primary and secondary glioblastomas.

http://www.wikidata.org/entity/Q27852506

description

2013 nî lūn-bûn

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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

TERT promoter mutations in primary and secondary glioblastomas.

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TERT promoter mutations in primary and secondary glioblastomas.

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TERT promoter mutations in primary and secondary glioblastomas.

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type

label

TERT promoter mutations in primary and secondary glioblastomas.

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TERT promoter mutations in primary and secondary glioblastomas.

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TERT promoter mutations in primary and secondary glioblastomas.

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prefLabel

TERT promoter mutations in primary and secondary glioblastomas.

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TERT promoter mutations in primary and secondary glioblastomas.

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TERT promoter mutations in primary and secondary glioblastomas.

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Acta Neuropathologica

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TERT promoter mutations in primary and secondary glioblastomas

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Hiroko Ohgaki

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Ji-Eun Oh

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Paul Kleihues

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Takashi Ohta

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Young-Ho Kim

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P2860

IDH1 and IDH2 mutations in gliomas

The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.

Specific association of human telomerase activity with immortal cells and cancer

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

Highly recurrent TERT promoter mutations in human melanoma

TERT promoter mutations in familial and sporadic melanoma

PROMO: detection of known transcription regulatory elements using species-tailored searches.

Telomere length modulation in human astroglial brain tumors

Genetic pathways to primary and secondary glioblastoma

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