Neuregulin 1 expression is a predictive biomarker for response to AV-203, an ERBB3 inhibitory antibody, in human tumor models.
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CIViC databaseERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1)Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121).Neuregulin expression in solid tumors: prognostic value and predictive role to anti-HER3 therapies.LJM716 in Japanese patients with head and neck squamous cell carcinoma or HER2-overexpressing breast or gastric cancer.HER3/ErbB3, an emerging cancer therapeutic target.Emerging anti-cancer antibodies and combination therapies targeting HER3/ERBB3.HER3 as a Therapeutic Target in Cancer.Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin.Clinical significance of overexpression of NRG1 and its receptors, HER3 and HER4, in gastric cancer patients.A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer.Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer.A comprehensive review of heregulins, HER3, and HER4 as potential therapeutic targets in cancer.NRG-1 Stimulates Serum DJ-1 Increase in Breast Cancers.Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non-small cell lung cancer.Successful targeting of the NRG1 pathway indicates novel treatment strategy for metastatic cancer.The immunoglobulin-like domain of neuregulins potentiates ErbB3/HER3 activation and cellular proliferation.Tumor evolution and chemoresistance in ovarian cancer
P2860
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P2860
Neuregulin 1 expression is a predictive biomarker for response to AV-203, an ERBB3 inhibitory antibody, in human tumor models.
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2015 nî lūn-bûn
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2015 թուականի Մարտին հրատարակուած գիտական յօդուած
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2015 թվականի մարտին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@ast
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@en
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@nl
type
label
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@ast
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@en
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@nl
prefLabel
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@ast
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@en
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@nl
P2093
P3181
P1476
Neuregulin 1 expression is a p ...... tibody, in human tumor models.
@en
P2093
Andrea R Delpero
Donna McIntosh
Elizabeth K Mazsa
Jeno Gyuris
Kristan Meetze
Richard Nicoletti
Solly Weiler
Steve Bottega
Steven Tyler
P304
P3181
P356
10.1158/1078-0432.CCR-14-2407
P407
P50
P577
2015-03-01T00:00:00Z