Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
about
Human metapneumovirus glycoprotein G inhibits innate immune responsesMDA-5 recognition of a murine norovirusZ proteins of New World arenaviruses bind RIG-I and interfere with type I interferon inductionHepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasionHepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunityToll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signalingDEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potentialCaspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I.Human metapneumovirus M2-2 protein inhibits innate cellular signaling by targeting MAVSATP-sensitive potassium channels mediate survival during infection in mammals and insectsHepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functionsCrystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modificationImmune signaling by RIG-I-like receptorsAnkrd17 positively regulates RIG-I-like receptor (RLR)-mediated immune signalingViral apoptosis is induced by IRF-3-mediated activation of BaxThe ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signalingA novel function of human Pumilio proteins in cytoplasmic sensing of viral infectionZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responsesNLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathwaysERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerizationThe autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunityRegulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.Peroxisomes are signaling platforms for antiviral innate immunityInhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virusPCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activationRIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediateNegative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinaseREUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-IRiplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infectionMDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signalingMitochondrially localised MUL1 is a novel modulator of antiviral signalingMAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune responseDDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signalingc-Abl tyrosine kinase interacts with MAVS and regulates innate immune responseSolution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptorsEbola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2
P2860
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P2860
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@ast
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@en
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@nl
type
label
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@ast
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@en
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@nl
prefLabel
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@ast
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@en
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@nl
P2093
P50
P3181
P356
P1433
P1476
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
@en
P2093
Andreas Jung
Chang-Sung Koh
Hiroki Kato
Kinya Otsu
Kosuke Matsui
Masahiro Yamamoto
Osamu Takeuchi
Osamu Yamaguchi
Satoshi Uematsu
Shintaro Sato
P2888
P3181
P356
10.1038/NATURE04734
P407
P577
2006-05-04T00:00:00Z
P5875
P6179
1012209674