Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists.
about
Molecular basis for negative regulation of the glucagon receptorInhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon ReceptorIncreased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretionAnti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonistRecent Progress in the Use of Glucagon and Glucagon Receptor Antago-nists in the Treatment of Diabetes MellitusGlucagon as a target for the treatment of Type 2 diabetes.Glucagon receptor antagonism induces increased cholesterol absorption.Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides.A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes.Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes.Glucagon antagonism as a potential therapeutic target in type 2 diabetes.A survey of small molecule glucagon receptor antagonists from recent patents (2006 - 2010).Glucagon actions on the kidney revisited: possible role in potassium homeostasis.Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis.The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin.Glucagon binds to Glucagon receptorPartial ablation of leptin signaling in mouse pancreatic α-cells does not alter either glucose or lipid homeostasis.
P2860
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P2860
Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists.
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@ast
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@en
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@nl
type
label
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@ast
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@en
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@nl
altLabel
Hepatic glucagon receptor bind ...... glucagon receptor antagonists
@en
prefLabel
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@ast
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@en
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@nl
P2093
P1476
Hepatic glucagon receptor bind ...... glucagon receptor antagonists.
@en
P2093
Bei B Zhang
Deborah Szalkowski
Edward Brady
Emma R Parmee
Guoqiang Jiang
Judith E Fenyk-Melody
Mari Rios Candelore
Mathias Strowski
Qing Dallas-Yang
Raymond E Gibson
P304
P356
10.1016/J.EJPHAR.2004.08.023
P407
P577
2004-10-06T00:00:00Z