Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment
about
The role of toxicological science in meeting the challenges and opportunities of hydraulic fracturingImplementing ecopharmacovigilance in practice: challenges and potential opportunitiesThe next generation of risk assessment multiyear study - highlights of findings, applications to risk assessment, and future directionsAnimal-Free Chemical Safety AssessmentIonotropic GABA receptor antagonism-induced adverse outcome pathways for potential neurotoxicity biomarkersCurrent perspectives on the use of alternative species in human health and ecological hazard assessmentsMolecular signaling network motifs provide a mechanistic basis for cellular threshold responsesBig data in chemical toxicity research: the use of high-throughput screening assays to identify potential toxicantsThe ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity TestingFrom the exposome to mechanistic understanding of chemical-induced adverse effectsUsing systematic reviews for hazard and risk assessment of endocrine disrupting chemicalsMechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP)Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision MakingThe Aryl Hydrocarbon Receptor: A Key Bridging Molecule of External and Internal Chemical SignalsSimilar anxiolytic effects of agonists targeting serotonin 5-HT1A or cannabinoid CB receptors on zebrafish behavior in novel environmentsConcern-driven integrated approaches to nanomaterial testing and assessment--report of the NanoSafety Cluster Working Group 10Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered NanomaterialsPredicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compoundsA proposal for assessing study quality: Biomonitoring, Environmental Epidemiology, and Short-lived Chemicals (BEES-C) instrumentDevelopmental neurotoxicity - challenges in the 21st century and in vitro opportunitiesAn in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterialsPutative adverse outcome pathways relevant to neurotoxicitySparking connections: toward better linkages between research and human health policy-an example with multiwalled carbon nanotubesMechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big DataDeveloping and applying the adverse outcome pathway concept for understanding and predicting neurotoxicityA new role for carbonic anhydrase 2 in the response of fish to copper and osmotic stress: implications for multi-stressor studiesExpert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials.Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge aheadTriclosan impairs swimming behavior and alters expression of excitation-contraction coupling proteins in fathead minnow (Pimephales promelas).High-Content Analysis Provides Mechanistic Insights into the Testicular Toxicity of Bisphenol A and Selected Analogues in Mouse Spermatogonial CellsTranscriptomics responses in marine diatom Thalassiosira pseudonana exposed to the polycyclic aromatic hydrocarbon benzo[a]pyreneAre pharmaceuticals with evolutionary conserved molecular drug targets more potent to cause toxic effects in non-target organisms?Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendiumQuantitative cross-species extrapolation between humans and fish: the case of the anti-depressant fluoxetineData-Driven Method to Estimate Nonlinear Chemical EquivalenceChemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver TranscriptomePredicting Fecundity of Fathead Minnows (Pimephales promelas) Exposed to Endocrine-Disrupting Chemicals Using a MATLAB®-Based Model of Oocyte Growth DynamicsFish connectivity mapping: linking chemical stressors by their mechanisms of action-driven transcriptomic profilesLiver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolismPerspectives on validation of high-throughput assays supporting 21st century toxicity testing
P2860
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P2860
Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Adverse outcome pathways: a co ...... y research and risk assessment
@ast
Adverse outcome pathways: a co ...... y research and risk assessment
@en
Adverse outcome pathways: a co ...... y research and risk assessment
@nl
type
label
Adverse outcome pathways: a co ...... y research and risk assessment
@ast
Adverse outcome pathways: a co ...... y research and risk assessment
@en
Adverse outcome pathways: a co ...... y research and risk assessment
@nl
prefLabel
Adverse outcome pathways: a co ...... y research and risk assessment
@ast
Adverse outcome pathways: a co ...... y research and risk assessment
@en
Adverse outcome pathways: a co ...... y research and risk assessment
@nl
P2093
P3181
P356
P1476
Adverse outcome pathways: a co ...... y research and risk assessment
@en
P2093
Christine L Russom
Dale J Hoff
Daniel L Villeneuve
David R Mount
Gerald T Ankley
John W Nichols
Jose A Serrrano
Joseph E Tietge
Michael W Hornung
Patricia K Schmieder
P304
P3181
P356
10.1002/ETC.34
P407
P577
2010-03-01T00:00:00Z