Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.
about
Conserved residues of human XPG protein important for nuclease activity and function in nucleotide excision repairHuman exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidanceThe RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activitiesMolecular interactions of human Exo1 with DNAArginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determinationStructural determinants for substrate binding and catalysis by the structure-specific endonuclease XPGHuman MUS81 complexes stimulate flap endonuclease 1Mutational analysis of the human nucleotide excision repair gene ERCC1Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodiesEssential amino acids for substrate binding and catalysis of human flap endonuclease 1Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complexOkazaki fragment maturation: nucleases take centre stageA common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: implications for a second XPG functionDouble strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamilyThe crystal structure of flap endonuclease-1 from Methanococcus jannaschiiEsc4/Rtt107 and the control of recombination during replication.Role of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination.Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigenDNA2 encodes a DNA helicase essential for replication of eukaryotic chromosomes.The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondriaCleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate.RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae.Involvement of Vts1, a structure-specific RNA-binding protein, in Okazaki fragment processing in yeast.Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27.Molecular mechanism of base excision repair of uracil-containing DNA in yeast cell-free extractsA yeast gene required for DNA replication encodes a protein with homology to DNA helicases.A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential functionAccessibility of DNA polymerases to repair synthesis during nucleotide excision repair in yeast cell-free extracts.Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loopsUnligated Okazaki Fragments Induce PCNA Ubiquitination and a Requirement for Rad59-Dependent Replication Fork Progression.Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulationThe general transcription-repair factor TFIIH is recruited to the excision repair complex by the XPA protein independent of the TFIIE transcription factorOverexpression and hypomethylation of flap endonuclease 1 gene in breast and other cancersIdentification of the XPG region that causes the onset of Cockayne syndrome by using Xpg mutant mice generated by the cDNA-mediated knock-in methodProliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stageMolecular cloning and structural analysis of the functional mouse genomic XPG genePostnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G geneDNA structural elements required for FEN-1 bindingMechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1
P2860
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P2860
Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Functional domains within FEN- ...... or nucleotide excision repair.
@ast
Functional domains within FEN- ...... or nucleotide excision repair.
@en
Functional domains within FEN- ...... or nucleotide excision repair.
@nl
type
label
Functional domains within FEN- ...... or nucleotide excision repair.
@ast
Functional domains within FEN- ...... or nucleotide excision repair.
@en
Functional domains within FEN- ...... or nucleotide excision repair.
@nl
altLabel
Functional domains within FEN- ...... for nucleotide excision repair
@en
prefLabel
Functional domains within FEN- ...... or nucleotide excision repair.
@ast
Functional domains within FEN- ...... or nucleotide excision repair.
@en
Functional domains within FEN- ...... or nucleotide excision repair.
@nl
P356
P1433
P1476
Functional domains within FEN- ...... or nucleotide excision repair.
@en
P2093
J J Harrington
M R Lieber
P304
P356
10.1101/GAD.8.11.1344
P407
P577
1994-06-01T00:00:00Z