Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5.
about
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongationArchitecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivityAn α Helix to β Barrel Domain Switch Transforms the Transcription Factor RfaH into a Translation FactorCdc73 Subunit of Paf1 Complex Contains C-terminal Ras-like Domain That Promotes Association of Paf1 Complex with ChromatinStructural basis for Spt5-mediated recruitment of the Paf1 complex to chromatinStructure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain foldThe C-terminal repeat domain of Spt5 plays an important role in suppression of Rad26-independent transcription coupled repair.Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.Uniform transitions of the general RNA polymerase II transcription complex.Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex.Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud.The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein.A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeastBiochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II ArrestHistone variant H2A.Z and RNA polymerase II transcription elongation.Ubiquitous transcription factors display structural plasticity and diverse functions: NusG proteins - Shifting shapes and paradigmsPhosphorylation of Not4p functions parallel to BUR2 to regulate resistance to cellular stresses in Saccharomyces cerevisiaeA positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeastSub1 associates with Spt5 and influences RNA polymerase II transcription elongation rateThe distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factorsProgression through the RNA polymerase II CTD cycleTransformation: the next level of regulation.DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genesThe transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress.RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases.H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFbInsights into how Spt5 functions in transcription elongation and repressing transcription coupled DNA repair.An investigation of a role for U2 snRNP spliceosomal components in regulating transcriptionSeparable functions of the fission yeast Spt5 carboxyl-terminal domain (CTD) in capping enzyme binding and transcription elongation overlap with those of the RNA polymerase II CTDRNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases.FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation.The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombinationSystematic analysis of protein phosphorylation networks from phosphoproteomic data.Functional analysis of Thermus thermophilus transcription factor NusGCDK9 and H2B monoubiquitination: a well-choreographed dance.Histone deacetylases and phosphorylated polymerase II C-terminal domain recruit Spt6 for cotranscriptional histone reassembly.The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeastTranscriptional regulation in Saccharomyces cerevisiae: transcription factor regulation and function, mechanisms of initiation, and roles of activators and coactivators.RNA polymerase II carboxyl-terminal domain phosphorylation regulates protein stability of the Set2 methyltransferase and histone H3 di- and trimethylation at lysine 36
P2860
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P2860
Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@ast
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@en
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@nl
type
label
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@ast
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@en
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@nl
prefLabel
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@ast
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@en
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@nl
P2093
P2860
P356
P1476
Control of transcriptional elo ...... ast BUR kinase substrate Spt5.
@en
P2093
Jack F Greenblatt
Jeffrey Fillingham
Wei Hung William Kuo
P2860
P304
P356
10.1073/PNAS.0806302106
P407
P577
2009-04-28T00:00:00Z