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Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2Finding the end: recruitment of telomerase to telomeresIn vivo veritas: using yeast to probe the biological functions of G-quadruplexesSaccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivoIntracellular trafficking of yeast telomerase components.Characterization of recombinant Saccharomyces cerevisiae telomerase core enzyme purified from yeast.TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeresEssential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interactionRvb2/reptin physically associates with telomerase in budding yeast.Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends.A bulged stem tethers Est1p to telomerase RNA in budding yeast.Biogenesis of yeast telomerase depends on the importin mtr10Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation.Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitmentSaccharomyces cerevisiae telomerase subunit Est3p binds DNA and RNA and stimulates unwinding of RNA/DNA heteroduplexes.Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNAInhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13pTen1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13RPA facilitates telomerase activity at chromosome ends in budding and fission yeastsTwo pathways recruit telomerase to Saccharomyces cerevisiae telomeresThe Saccharomyces cerevisiae telomerase subunit Est3 binds telomeres in a cell cycle- and Est1-dependent manner and interacts directly with Est1 in vitroThe TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisCell cycle-dependent regulation of yeast telomerase by Ku.Euplotes telomerase contains an La motif protein produced by apparent translational frameshiftingN-terminal domain of yeast telomerase reverse transcriptase: recruitment of Est3p to the telomerase complexYeast telomerase is specialized for C/A-rich RNA templates.A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro.Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency.Tetrahymena proteins p80 and p95 are not core telomerase components.Identification of human TERT elements necessary for telomerase recruitment to telomeres.Delineation of the high-affinity single-stranded telomeric DNA-binding domain of Saccharomyces cerevisiae Cdc13.Investigating the role of the Est3 protein in yeast telomere replication.Functional multimerization of the human telomerase reverse transcriptase.Molecular basis for telomere repeat divergence in budding yeastN-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo.The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeresThe biogenesis and regulation of telomerase holoenzymesNormal telomere length maintenance in Saccharomyces cerevisiae requires nuclear import of the ever shorter telomeres 1 (Est1) protein via the importin alpha pathway.Regulated assembly and disassembly of the yeast telomerase quaternary complex.Analysis of telomerase in Candida albicans: potential role in telomere end protection
P2860
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P248
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The Est3 protein is a subunit of yeast telomerase.
@ast
The Est3 protein is a subunit of yeast telomerase.
@en
The Est3 protein is a subunit of yeast telomerase.
@nl
type
label
The Est3 protein is a subunit of yeast telomerase.
@ast
The Est3 protein is a subunit of yeast telomerase.
@en
The Est3 protein is a subunit of yeast telomerase.
@nl
prefLabel
The Est3 protein is a subunit of yeast telomerase.
@ast
The Est3 protein is a subunit of yeast telomerase.
@en
The Est3 protein is a subunit of yeast telomerase.
@nl
P2093
P3181
P1433
P1476
The Est3 protein is a subunit of yeast telomerase.
@en
P2093
R G Weilbaecher
T R Hughes
V Lundblad
P304
P3181
P356
10.1016/S0960-9822(00)00562-5
P407
P577
2000-06-29T00:00:00Z