TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
about
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4Sister chromatid decatenation: bridging the gaps in our knowledgePICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosisDisruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.Mitotic catenation is monitored and resolved by a PKCε-regulated pathwayATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission.Rescue from replication stress during mitosis.TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution.Interplay between histone H3 lysine 56 deacetylation and chromatin modifiers in response to DNA damage.Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA.Centromere pairing--tethering partner chromosomes in meiosis I.Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination.Human CST abundance determines recovery from diverse forms of DNA damage and replication stress.Rif1 Regulates the Fate of DNA Entanglements during Mitosis.The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA SegregationIncision of damaged DNA in the presence of an impaired Smc5/6 complex imperils genome stabilityCell cycle regulation of homologous recombination in Saccharomyces cerevisiae.Cdc14 phosphatase: warning, no delay allowed for chromosome segregation!PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction.TopBP1-mediated DNA processing during mitosis.Multi-BRCT scaffolds use distinct strategies to support genome maintenance.Mutagenic Potential ofBos taurus Papillomavirus Type 1 E6 Recombinant Protein: First Description.The Slx4-Dpb11 scaffold complex: coordinating the response to replication fork stalling in S-phase and the subsequent mitosis.A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication.Genome-Scale Genetic Interactions and Cell Imaging Confirm Cytokinesis as Deleterious to Transient Topoisomerase II Deficiency in Saccharomyces cerevisiae.MCPH1, mutated in primary microcephaly, is required for efficient chromosome alignment during mitosis.TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells.TopBP1 makes the final call for repair on the verge of cell division.Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations.Imaging of DNA Ultrafine Bridges in Budding Yeast.Observing Mitotic Division and Dynamics in a Live Zebrafish Embryo.A New Way to Treat Brain Tumors: Targeting Proteins Coded by Microcephaly Genes?: Brain tumors and microcephaly arise from opposing derangements regulating progenitor growth. Drivers of microcephaly could be attractive brain tumor targets.The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress.Sending sisters their separate ways.
P2860
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P2860
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2013年の論文
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TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
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TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
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TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
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label
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
@ast
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
@en
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
@nl
prefLabel
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
@ast
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
@en
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
@nl
P2860
P50
P3181
P356
P1476
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.
@en
P2093
Nadine Eckert-Boulet
Vera Schramke
P2860
P3181
P356
10.1083/JCB.201305157
P407
P577
2013-12-30T00:00:00Z