The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein
about
The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturationA yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcriptsC1D family proteins in coordinating RNA processing, chromosome condensation and DNA damage responseNuclear noncoding RNA surveillance: is the end in sight?Activities of human RRP6 and structure of the human RRP6 catalytic domainCrystal Structure of a 9-Subunit Archaeal Exosome in Pre-Catalytic States of the Phosphorolytic ReactionRRP6 from Trypanosoma brucei: crystal structure of the catalytic domain, association with EAP3 and activity towards structured and non-structured RNA substratesStructure of an Rrp6–RNA exosome complex bound to poly(A) RNAEvidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.Assembly of the yeast exoribonuclease Rrp6 with its associated cofactor Rrp47 occurs in the nucleus and is critical for the controlled expression of Rrp47Exosome Cofactors Connect Transcription Termination to RNA Processing by Guiding Terminated Transcripts to the Appropriate Exonuclease within the Nuclear ExosomeThe essential nucleolar yeast protein Nop8p controls the exosome function during 60S ribosomal subunit maturationThe Sm complex is required for the processing of non-coding RNAs by the exosomeThe CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome.Comparison of the yeast and human nuclear exosome complexes.The exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae.Nab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1Exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the noncatalytic core and central channel.Degradation of a polyadenylated rRNA maturation by-product involves one of the three RRP6-like proteins in Arabidopsis thaliana.RNA recognition by 3'-to-5' exonucleases: the substrate perspective.Exonucleolysis is required for nuclear mRNA quality control in yeast THO mutantsThe Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome.Structure and Activities of the Eukaryotic RNA Exosome.The eukaryotic RNA exosomeYeast nuclear RNA processing.mRNA quality control pathways in Saccharomyces cerevisiae.Exosome substrate targeting: the long and short of it.The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.Comparison of preribosomal RNA processing pathways in yeast, plant and human cells - focus on coordinated action of endo- and exoribonucleases.Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase.Cotranscriptional recruitment of RNA exosome cofactors Rrp47p and Mpp6p and two distinct Trf-Air-Mtr4 polyadenylation (TRAMP) complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant messenger ribonucleoprotein particlRrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6.Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex
P2860
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P2860
The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The PMC2NT domain of the catal ...... a nucleic acid-binding protein
@ast
The PMC2NT domain of the catal ...... a nucleic acid-binding protein
@en
The PMC2NT domain of the catal ...... nucleic acid-binding protein.
@nl
type
label
The PMC2NT domain of the catal ...... a nucleic acid-binding protein
@ast
The PMC2NT domain of the catal ...... a nucleic acid-binding protein
@en
The PMC2NT domain of the catal ...... nucleic acid-binding protein.
@nl
prefLabel
The PMC2NT domain of the catal ...... a nucleic acid-binding protein
@ast
The PMC2NT domain of the catal ...... a nucleic acid-binding protein
@en
The PMC2NT domain of the catal ...... nucleic acid-binding protein.
@nl
P2093
P2860
P356
P1476
The PMC2NT domain of the catal ...... a nucleic acid-binding protein
@en
P2093
Joe L Costello
Jonathan A Stead
Michaela J Livingstone
Phil Mitchell
P2860
P304
P356
10.1093/NAR/GKM614
P407
P577
2007-01-01T00:00:00Z