Prion-impairing mutations in Hsp70 chaperone Ssa1: effects on ATPase and chaperone activities.
about
Clathrin coat disassembly by the yeast Hsc70/Ssa1p and auxilin/Swa2p proteins observed by single-particle burst analysis spectroscopy.Using steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagationThe mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free systemDestabilization and recovery of a yeast prion after mild heat shock.Single methyl group determines prion propagation and protein degradation activities of yeast heat shock protein (Hsp)-70 chaperones Ssa1p and Ssa2pFunctions of yeast Hsp40 chaperone Sis1p dispensable for prion propagation but important for prion curing and protection from prion toxicity.Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions.Structural variants of yeast prions show conformer-specific requirements for chaperone activity.Influence of Hsp70s and their regulators on yeast prion propagationDesigner protein disaggregases to counter neurodegenerative disease.Ssa1 overexpression and [PIN(+)] variants cure [PSI(+)] by dilution of aggregates.The β6/β7 region of the Hsp70 substrate-binding domain mediates heat-shock response and prion propagation.
P2860
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P2860
Prion-impairing mutations in Hsp70 chaperone Ssa1: effects on ATPase and chaperone activities.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Prion-impairing mutations in H ...... Pase and chaperone activities.
@ast
Prion-impairing mutations in H ...... Pase and chaperone activities.
@en
Prion-impairing mutations in H ...... Pase and chaperone activities.
@nl
type
label
Prion-impairing mutations in H ...... Pase and chaperone activities.
@ast
Prion-impairing mutations in H ...... Pase and chaperone activities.
@en
Prion-impairing mutations in H ...... Pase and chaperone activities.
@nl
prefLabel
Prion-impairing mutations in H ...... Pase and chaperone activities.
@ast
Prion-impairing mutations in H ...... Pase and chaperone activities.
@en
Prion-impairing mutations in H ...... Pase and chaperone activities.
@nl
P2860
P921
P1476
Prion-impairing mutations in H ...... Pase and chaperone activities.
@en
P2093
Daniel C Masison
Patrick G Needham
P2860
P304
P356
10.1016/J.ABB.2008.07.023
P407
P577
2008-10-15T00:00:00Z