Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity.
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An internal GAP domain negatively regulates presynaptic dynamin in vivo: a two-step model for dynamin functionWhy is start codon selection so precise in eukaryotes?'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)Molecular architecture of a eukaryotic translational initiation complex.eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joiningStructure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNAX-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1AInteraction between eukaryotic initiation factors 1A and 5B is required for efficient ribosomal subunit joining.rRNA suppressor of a eukaryotic translation initiation factor 5B/initiation factor 2 mutant reveals a binding site for translational GTPases on the small ribosomal subunit.Structural integrity of {alpha}-helix H12 in translation initiation factor eIF5B is critical for 80S complex stability.Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance.Domain and nucleotide dependence of the interaction between Saccharomyces cerevisiae translation elongation factors 3 and 1A.Coupled release of eukaryotic translation initiation factors 5B and 1A from 80S ribosomes following subunit joining.Regulation of translation initiation in eukaryotes: mechanisms and biological targetsTwo RNA-binding motifs in eIF3 direct HCV IRES-dependent translationA mechanistic overview of translation initiation in eukaryotesMolecular mechanisms of translational controlSelenocysteine tRNA-specific elongation factor SelB is a structural chimaera of elongation and initiation factorsDrosophila rolling blackout displays lipase domain-dependent and -independent endocytic functions downstream of dynamin.The roles of initiation factor 2 and guanosine triphosphate in initiation of protein synthesisPhylogenetic distribution of translational GTPases in bacteriaThe eukaryotic initiation factor (eIF) 4G HEAT domain promotes translation re-initiation in yeast both dependent on and independent of eIF4A mRNA helicaseThe mechanism of eukaryotic translation initiation: new insights and challengesRoles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAseIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning.Eukaryotic translation initiation factor 5 is critical for integrity of the scanning preinitiation complex and accurate control of GCN4 translation.Interaction of the RNP1 motif in PRT1 with HCR1 promotes 40S binding of eukaryotic initiation factor 3 in yeastComponents of the multifactor complex needed for internal initiation by the IRES of hepatitis C virus in Saccharomyces cerevisiaeIntragenic suppressor mutations restore GTPase and translation functions of a eukaryotic initiation factor 5B switch II mutant.Reconfiguration of yeast 40S ribosomal subunit domains by the translation initiation multifactor complex.Protein synthesis during cellular quiescence is inhibited by phosphorylation of a translational elongation factor.Rapid Discovery of Functional Small Molecule Ligands against Proteomic Targets through Library-Against-Library Screening.Evidence for a Negative Cooperativity between eIF5A and eEF2 on Binding to the RibosomeCofactor dependent conformational switching of GTPases.Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae.Interaction between 25S rRNA A loop and eukaryotic translation initiation factor 5B promotes subunit joining and ensures stringent AUG selection.Kinetic analysis of late steps of eukaryotic translation initiationFunctions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control.Poliovirus switches to an eIF2-independent mode of translation during infection.Sliding of a 43S ribosomal complex from the recognized AUG codon triggered by a delay in eIF2-bound GTP hydrolysis
P2860
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P2860
Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Uncoupling of initiation facto ...... that lower ribosome affinity.
@ast
Uncoupling of initiation facto ...... that lower ribosome affinity.
@en
Uncoupling of initiation facto ...... that lower ribosome affinity.
@nl
type
label
Uncoupling of initiation facto ...... that lower ribosome affinity.
@ast
Uncoupling of initiation facto ...... that lower ribosome affinity.
@en
Uncoupling of initiation facto ...... that lower ribosome affinity.
@nl
prefLabel
Uncoupling of initiation facto ...... that lower ribosome affinity.
@ast
Uncoupling of initiation facto ...... that lower ribosome affinity.
@en
Uncoupling of initiation facto ...... that lower ribosome affinity.
@nl
P2093
P50
P3181
P1433
P1476
Uncoupling of initiation facto ...... that lower ribosome affinity.
@en
P2093
Byung-Sik Shin
David Maag
M Shamsul Arefin
P304
P3181
P356
10.1016/S0092-8674(02)01171-6
P407
P577
2002-12-27T00:00:00Z