Inhibition of a spliceosome turnover pathway suppresses splicing defects.
about
Functional roles of DExD/H-box RNA helicases in Pre-mRNA splicingRNA helicases in splicingSplicing fidelity: DEAD/H-box ATPases as molecular clocksMechanism for Aar2p function as a U5 snRNP assembly factorStructural basis for dual roles of Aar2p in U5 snRNP assemblyCwc23, an essential J protein critical for pre-mRNA splicing with a dispensable J domainConserved interactions of the splicing factor Ntr1/Spp382 with proteins involved in DNA double-strand break repair and telomere metabolism.The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosomeThe G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosomeIdentification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassemblyTFIP11 interacts with mDEAH9, an RNA helicase involved in spliceosome disassemblySpliceosome Structure and FunctionThe HSP70 chaperone machinery: J proteins as drivers of functional specificityDistinct roles of non-canonical poly(A) polymerases in RNA metabolism.Spliceosome discards intermediates via the DEAH box ATPase Prp43p.DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps.Proofreading and spellchecking: a two-tier strategy for pre-mRNA splicing quality control.A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release.Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation.NTR1 is required for transcription elongation checkpoints at alternative exons in ArabidopsisLimited portability of G-patch domains in regulators of the Prp43 RNA helicase required for pre-mRNA splicing and ribosomal RNA maturation in Saccharomyces cerevisiae.Functional roles of protein splicing factors.Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassemblyLink of NTR-mediated spliceosome disassembly with DEAH-box ATPases Prp2, Prp16, and Prp22.The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein functionThe spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine.Staying on message: ensuring fidelity in pre-mRNA splicing.Regulation of Prp43-mediated disassembly of spliceosomes by its cofactors Ntr1 and Ntr2Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system.The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction.Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry.The splice is right: guarantors of fidelity in pre-mRNA splicingStructural insights into the mechanism of the DEAH-box RNA helicase Prp43Cwc23 is a component of the NTR complex and functions to stabilize Ntr1 and facilitate disassembly of spliceosome intermediates.
P2860
Q26801902-40717F1D-6700-4BBD-9FE6-B32D1B265713Q27000261-AB89B6DC-E895-4736-9F2F-7F540E9D74AEQ27008926-828D1005-0387-4F1E-BADE-ECF7D2EFAFC5Q27670833-032D461D-9F05-4A12-955E-E5D9DE36A72CQ27676636-3A6CB211-73CE-42ED-A01A-7A36BDB10E3DQ27929874-6D1DCBF5-2793-4BD9-AFE3-A3E5370F53A5Q27930755-715C5D7B-4EF0-4141-925B-C731976AB9E7Q27933083-D23D5D33-438D-42D2-92A2-3FA75A306AF7Q27936960-3CF50BD9-FFBD-4B2A-A898-12D451630080Q27938864-37B4401E-38AE-46CC-91C8-66BBE8227B06Q28506110-98FC304B-D4C1-4777-8AE8-FB280110CBFFQ28513812-24F3FEF2-B3B0-4B1E-B5EF-03EE33EC78E2Q29392298-16F61FC7-9550-4059-AAD7-A0081A110A7BQ29616140-97168338-5740-41DA-815E-3454C57724D0Q33480938-838A3CE1-AE52-43E0-888F-3DFA60397D5AQ33933327-FD18FF44-D201-4805-B0D1-DF144A63A338Q34415414-954E6839-EA25-4264-B672-504947A0E983Q34574841-4F6678E1-BE67-4C50-AF33-5A83B1059123Q34788134-936D6612-7FCF-4BC8-A5BC-34D054701DE5Q34887390-54B6DB78-52D8-4509-83F2-E0D892E77B6DQ35090680-0C5B5280-57B9-4A8D-BAA0-A643A322CBB5Q35579775-B7F6D855-0D02-475D-B996-DAF8509514A8Q36083004-2EB69EB1-F661-4E4D-8E35-CB51B46FD220Q36315971-F091A016-FBF6-45C5-AC91-635AC8833559Q36560014-4100463D-0CE0-4C84-96C1-C83657BD8611Q37043127-65D405B5-ED94-4BC4-B4D0-E7B993CD43B6Q37197189-FCC04553-F476-4481-AF95-33B3881CC4BCQ37351792-C4BA74D4-EF2A-45B6-BFBF-7B4FE2E5BA03Q37809832-15AE2D21-F975-481B-A221-1592F024F36BQ38008056-AD4524F9-DC8F-48A0-BA25-55AF7166AB65Q39125817-3014CA85-DF15-46B0-B7DF-E4645A52D8B7Q41553559-A7D0E5A1-C10B-4F0D-AE27-AF022F2CD7B5Q41558357-5A3B5AEF-24FC-4904-B0E9-72ADE0E48750Q41890783-6427A68E-8307-4E94-97C4-1CE284832BEFQ42063265-63D9945A-B9E9-4B17-AF88-CFC5F8717473Q42328217-B5C3029C-2924-4590-82F3-7ED8F5872251Q49489493-3C98569F-C104-454A-A047-87143653264B
P2860
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@ast
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@en
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@nl
type
label
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@ast
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@en
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@nl
prefLabel
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@ast
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@en
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@nl
P2093
P2860
P3181
P356
P1476
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
@en
P2093
Brian C Rymond
Shatakshi Pandit
P2860
P304
P3181
P356
10.1073/PNAS.0603188103
P407
P577
2006-09-12T00:00:00Z