The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis.
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A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiencyCOQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration.Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase.Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complexIdentification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiaeOverexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humansCoenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6Human COQ9 Rescues a coq9 Yeast Mutant by Enhancing Coenzyme Q Biosynthesis from 4-Hydroxybenzoic Acid and Stabilizing the CoQ-SynthomeEffects of inhibiting CoQ10 biosynthesis with 4-nitrobenzoate in human fibroblasts.A germline missense mutation in COQ6 is associated with susceptibility to familial schwannomatosis.Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana.Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis.Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesisGenetic evidence for an interaction of the UbiG O-methyltransferase with UbiX in Escherichia coli coenzyme Q biosynthesis.Yeast Coq9 controls deamination of coenzyme Q intermediates that derive from para-aminobenzoic acid.Endogenous synthesis of coenzyme Q in eukaryotes.Primary congenital glaucoma localizes to chromosome 14q24.2-24.3 in two consanguineous Pakistani families.Evolution of Ubiquinone Biosynthesis: Multiple Proteobacterial Enzymes with Various Regioselectivities To Catalyze Three Contiguous Aromatic Hydroxylation Reactions.Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants.Cellular factories for coenzyme Q10 production.Coenzyme Q10 deficiencies in neuromuscular diseases.Regulation of coenzyme Q biosynthesis in yeast: a new complex in the block.Biosynthesis of coenzyme Q in eukaryotes.The regulation of coenzyme q biosynthesis in eukaryotic cells: all that yeast can tell us.Coq6 is responsible for the C4-deamination reaction in coenzyme Q biosynthesis in Saccharomyces cerevisiae.Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity.Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.A two-component hydroxylase involved in the assimilation of 3-hydroxyphenyl acetate in Pseudomonas putida.Biochemistry of Mitochondrial Coenzyme Q Biosynthesis.DHB is hydroxylated to DHDB by COQ6DMPhOH is hydroxylated to MDMQ10H2 by DMPhOH monooxygenaseGenome-based analysis for the identification of genes involved in o-xylene degradation in Rhodococcus opacus R7
P2860
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P2860
The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis.
description
2003 nî lūn-bûn
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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2003 թվականի հուլիսին հրատարակված գիտական հոդված
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年學術文章
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name
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@ast
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@en
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@nl
type
label
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@ast
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@en
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@nl
prefLabel
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@ast
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@en
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@nl
P2093
P2860
P3181
P356
P1476
The Saccharomyces cerevisiae C ...... d for coenzyme Q biosynthesis.
@en
P2093
Adam Y Hsu
Catherine F Clarke
Peter T Lee
Steven C Rothman
Tanya Jonassen
P2860
P304
P3181
P356
10.1074/JBC.M303234200
P407
P577
2003-07-11T00:00:00Z